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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">therapeutic</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский журнал терапевтической практики</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Therapeutic Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8156</issn><issn pub-type="epub">3033-8344</issn><publisher><publisher-name>РостГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2712-8156-2021-2-1-8-16</article-id><article-id custom-type="elpub" pub-id-type="custom">therapeutic-118</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Перспективы терапии центрального апноэ сна и дыхания Чейн-Стокса при сердечной недостаточности</article-title><trans-title-group xml:lang="en"><trans-title>Prospects for the treatment of central sleep apnea and Cheyne-Stokes respiration in heart failure</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3758-5850</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алехина</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Alyokhina</surname><given-names>Y. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алехина Юлия Вадимовна - студентка факультета фундаментальной медицины.</p><p>Москва</p></bio><bio xml:lang="en"><p>Yulia V. Alyokhina, student of the Fundamental Medicine Faculty.</p><p>Moscow</p></bio><email xlink:type="simple">alekhjuliet97@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1490-2078</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Середенина</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Seredenina</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Середенина Елена Михайловна - кандидат медицинских наук, старший научный сотрудник отдела возраст-ассоциированных заболеваний.</p><p>Москва</p></bio><bio xml:lang="en"><p>Elena M. Seredenina, Cand. Sci. (Med.), leading researcher of the Department of Age-Related Diseases.</p><p>Moscow</p></bio><email xlink:type="simple">e.m.seredenina@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5324-4733</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калинкин</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalinkin</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Калинкин Александр Леонидович - руководитель центра медицины сна, ведущий научный сотрудник отдела воз-раст-ассоциированных заболеваний.</p><p>Москва</p></bio><bio xml:lang="en"><p>Alexander L. Kalinkin, Head of the Sleep Medicine Center of the Lomonosov Moscow State University Clinic, leading researcher of the Department of Age-Related Diseases.</p><p>Moscow</p></bio><email xlink:type="simple">akalinkin@sleeplab.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Московский государственный университет имени М.В. Ломоносова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Lomonosov Moscow State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Медицинский научно-образовательный центр МГУ имени М.В. Ломоносова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Lomonosov Moscow State University Clinic</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>23</day><month>03</month><year>2021</year></pub-date><volume>2</volume><issue>1</issue><fpage>8</fpage><lpage>16</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алехина Ю.В., Середенина Е.М., Калинкин А.Л., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Алехина Ю.В., Середенина Е.М., Калинкин А.Л.</copyright-holder><copyright-holder xml:lang="en">Alyokhina Y.V., Seredenina E.M., Kalinkin A.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therapeutic-j.ru/jour/article/view/118">https://www.therapeutic-j.ru/jour/article/view/118</self-uri><abstract><p>В этом обзоре обсуждаются факторы риска, клинические проявления, патофизиология, диагностика и варианты лечения центрального апноэ сна и дыхания Чейна-Стокса у пациентов с сердечной недостаточностью. Обсуждаются эффективность и перспективы терапевтических методов, таких как «сипап»-терапия, адаптивная сервовентиляция, трансвенозная стимуляция диафрагмального нерва.</p></abstract><trans-abstract xml:lang="en"><p>The risk factors, clinical manifestations, pathophysiology, diagnosis and treatment options for central sleep apnea and Cheyne-Stokes respiration in patients with heart failure are highlighted in this review. The effectiveness and prospects of therapeutic approaches are discussed: CPAP therapy, adaptive servo ventilation, transvenous stimulation of the phrenic nerve.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дыхание Чейна-Стокса</kwd><kwd>центральное апноэ сна</kwd><kwd>«сипап»-терапия</kwd><kwd>адаптивная сервовентиляция</kwd><kwd>трансвенозная стимуляция диафрагмального нерва</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Cheyne-Stokes respiration</kwd><kwd>central sleep apnea</kwd><kwd>continuous positive airway pressure therapy</kwd><kwd>adaptive servo-ventilation therapy</kwd><kwd>transvenous stimulation of the phrenic nerve</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Maggioni AP, Dahlstrom U, Filippatos G, Chioncel O, Crespo Leiro M, Drozdz J, et al. 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