therapeuticЮжно-Российский журнал терапевтической практикиSouth Russian Journal of Therapeutic Practice2712-81563033-8344РостГМУ10.21886/2712-8156-2021-2-3-6-17therapeutic-169Research ArticleОБЗОРЫREVIEWSОстрое повреждение почек у пациентов с хронической сердечной недостаточностьюAcute kidney injury in patients with chronic heart failurehttps://orcid.org/0000-0003-1180-3549АрутюновА. Г.ArutyunovA. G.

Арутюнов Александр Григорьевич, д.м.н., профессор кафедры пропедевтики внутренних болезней педиатрического факультета;

генеральный секретарь

Москва

Alexander G. Arutyunov, Dr. Sci. (Med.), Professor of Department of Internal Medicine Propaedeutics of the Pediatric Faculty;

General secretary

Moscow

agarutyunov@mail.ruhttps://orcid.org/0000-0001-9344-1304БашкиновР. А.BashkinovR. A.

Башкинов Роман Андреевич, медицинский советник

Москва

Roman A. Bashkinov, Medical advisor

Moscow

bashkinov-roman@mail.ruhttps://orcid.org/0000-0002-0210-2321БатлукТ. И.BatlukT. I.

Батлук Татьяна Ивановна, к.м.н., ассистент кафедры пропедевтики внутренних болезней педиатрического факультета;

Медицинский советник

Москва

Tatiana I. Batluk, Cand. Sci. (Med.), Assistant of Department of Internal Medicine Propaedeutics of the Pediatric Faculty;

Medical advisor

Moscow

tatianabatluk92@gmail.comhttps://orcid.org/0000-0002-8521-6542МельниковЕ. С.MelnikovE. S.

Мельников Евгений Сергеевич, медицинский советник

Москва

Evgeny S. Melnikov, Medical advisor

Moscow

melnikovzhenya@mail.ruhttps://orcid.org/0000-0002-5704-697XЕрмиловаА. Н.ErmilovaA. N.

Ермилова Анастасия Николаевна, медицинский советник

Москва

Anastasia N. Ermilova, Medical advisor

Moscow

linkrain1@gmail.comФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России; «Евразийская Ассоциация Терапевтов»РоссияPirogov Russian National Research Medical University; “Eurasian Association of Therapists”Russian Federation«Евразийская Ассоциация Терапевтов»Россия“Eurasian Association of Therapists”Russian Federation"Евразийская Ассоциация Терапевтов"Россия“Eurasian Association of Therapists”Russian Federation20212908202123617Copyright © Арутюнов А.Г., Башкинов Р.А., Батлук Т.И., Мельников Е.С., Ермилова А.Н., 20212021Арутюнов А.Г., Башкинов Р.А., Батлук Т.И., Мельников Е.С., Ермилова А.Н.Arutyunov A.G., Bashkinov R.A., Batluk T.I., Melnikov E.S., Ermilova A.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.therapeutic-j.ru/jour/article/view/169

Проблема хронической сердечной недостаточности (ХСН), а особенно ХСН со сниженной фракцией выброса является одной из наиболее значимых для современных систем здравоохранения. Это обусловлено высокой смертностью, сниженным качеством жизни, частыми эпизодами госпитализаций и выраженной коморбидностью пациентов с данной патологией. Вовлечение в патологический процесс почек является одним из наиболее встречаемых коморбидных состояний при сердечно-сосудистых заболеваниях. Имеется большое количество патогенетических механизмов взаимнонегативного влияния сердечной недостаточности и нарушения функции почек, нашедших отражение в понятии «кардиоренальный синдром». Более того, медикаментозная терапия ХСН может быть одной из причин поражения почек. Особенно угрожаемыми состояниями являются эпизоды острой декомпенсации кровообращения, а также новая коронавирусная инфекция (COVID-19). Целью данного обзора является консолидация имеющихся в международной литературе данных о проблеме острого повреждения почек у пациентов с ХСН. Проблема хронической сердечной недостаточности (ХСН), а особенно ХСН со сниженной фракцией выброса является одной из наиболее значимых для современных систем здравоохранения. Это обусловлено высокой смертностью, сниженным качеством жизни, частыми эпизодами госпитализаций и выраженной коморбидностью пациентов с данной патологией. Вовлечение в патологический процесс почек является одним из наиболее встречаемых коморбидных состояний при сердечно-сосудистых заболеваниях. Имеется большое количество патогенетических механизмов взаимнонегативного влияния сердечной недостаточности и нарушения функции почек, нашедших отражение в понятии «кардиоренальный синдром». Более того, медикаментозная терапия ХСН может быть одной из причин поражения почек. Особенно угрожаемыми состояниями являются эпизоды острой декомпенсации кровообращения, а также новая коронавирусная инфекция (COVID-19). Целью данного обзора является консолидация имеющихся в международной литературе данных о проблеме острого повреждения почек у пациентов с ХСН.

The problem of chronic heart failure (CHF) and especially CHF with reduced ejection fraction is one of the most significant for modern healthcare systems. This is due to the high mortality rate, reduced quality of life, frequent hospitalizations and marked comorbidity of patients with this pathology. Involvement of the kidneys in the pathological process is one of the most common comorbid conditions in cardiovascular disease. There are a large number of pathogenetic mechanisms of mutually negative impact of heart failure and renal dysfunction, reflected in the concept of «Cardiorenal syndrome». Moreover, drug therapy of CHF can be one of the causes of kidney damage. Episodes of acute circulatory decompensation as well as a new coronavirus infection (COVID-19) are particularly threatening conditions. The aim of this review is to consolidate the international literature on the problem of acute kidney injury in patients with CHF.

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The authors declare that there are no conflicts of interest present.