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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">therapeutic</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский журнал терапевтической практики</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Therapeutic Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8156</issn><issn pub-type="epub">3033-8344</issn><publisher><publisher-name>РостГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2712-8156-2021-2-4-96-100</article-id><article-id custom-type="elpub" pub-id-type="custom">therapeutic-190</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Интерстициальное поражение лёгких, вызванное применением увлажнителя воздуха</article-title><trans-title-group xml:lang="en"><trans-title>Clinical observation of interstitial lung injury caused by the use of humidifier</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7464-826X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кароли</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Karoli</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кароли Нина Анатольевна, доктор медицинских наук профессор кафедры госпитальной терапии лечебного факультета</p><p>Саратов</p></bio><bio xml:lang="en"><p>Nina A. Karoli, Dr. Sci. (Med.), professor of hospital therapy chair of general medicine Department</p><p>Saratov</p></bio><email xlink:type="simple">nina.karoli.73@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8820-351X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Харламов</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Kharlamov</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Харламов Виктор Евгеньевич, ординатор кафедры гoспитальной терапии лечебнoго факультета</p><p>Саратов</p></bio><bio xml:lang="en"><p>Viktor E. Kharlamov, resident of the department of hospital therapy</p><p>Saratov</p></bio><email xlink:type="simple">viktor-stone@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0201-7757</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зарманбетова</surname><given-names>О. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Zarmanbetova</surname><given-names>O. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зарманбетова Оьтебике Таймасхановна, врач-терапевт</p><p>Саратов</p></bio><bio xml:lang="en"><p>Otebike T. Zarmanbetova, therapeutist</p><p>Saratov</p></bio><email xlink:type="simple">o.umartova2013@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Сaратовский государствeнный мeдицинский унивeрситет им. В.И. Разумoвского Минздрава Рoссии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>2Clinical Hospital” Russian Railways-Medicine of the city of Saratov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ЧУЗ «Клиническая больница «РЖД-Медицина» города Саратова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical Hospital ”Russian Railways-Medicine of the city of Saratov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>02</day><month>12</month><year>2021</year></pub-date><volume>2</volume><issue>4</issue><fpage>96</fpage><lpage>100</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кароли Н.А., Харламов В.Е., Зарманбетова О.Т., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Кароли Н.А., Харламов В.Е., Зарманбетова О.Т.</copyright-holder><copyright-holder xml:lang="en">Karoli N.A., Kharlamov V.E., Zarmanbetova O.T.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therapeutic-j.ru/jour/article/view/190">https://www.therapeutic-j.ru/jour/article/view/190</self-uri><abstract><p>Синдром Humidifier lung -это редкий фенотип гиперчувствительного пневмонита (ГП), вызываемый вдыханием паров загрязненных климатических приборов, таких как увлажнитель воздуха и кондиционер. Так как описанный синдром редко встречается в РФ, практикующий врач должен проявлять настороженность отношении данной патологии, тщательно собирать анамнез у пациента, а также проводить дифференциальную диагностику с поражениями лёгких аутоиммунного, лекарственного, инфекционного генеза. Терапия ГП включает в себя исключение контакта с этиологическим фактором и назначение системной гормональной терапии.</p></abstract><trans-abstract xml:lang="en"><p>Humidifier lung syndrome is a rare phenotype of hypersensitive pneumonitis (HP) caused by inhalation of fumes from contaminated climate appliances such as a humidifier and air conditioner. Since the described syndrome is rarely found in the Russian Federation, the practitioner should be wary of this pathology, carefully collect an anamnesis from the patient, and also carry out differential diagnostics with lung lesions of autoimmune, drug, infectious genesis. HP therapy includes exclusion of contact with the etiological factor and the appointment of systemic hormonal therapy.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>гиперчувствительный пневмонит</kwd><kwd>увлажнитель воздуха</kwd><kwd>интерстициальное поражение легких</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypersensitive pneumonitis</kwd><kwd>humidifier</kwd><kwd>intersitial lung disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Авдеев С.Н. Гиперчувствительный пневмонит. Пульмонология. 2021;31(1):83-94. DOI: 10.18093/0869-0189-2021-31-1-1-128.</mixed-citation><mixed-citation xml:lang="en">Avdeev S.N. Hypersensitivity pneumonitis. Pul'monologiya. 2021; 31 (1): 83-94. (in Russian)].</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Raghu G, Remy-Jardin M, Ryerson CJ, Myers JL, Kreuter M, Vasakova M, et al. Diagnosis of Hypersensitivity Pneumonitis in Adults. An Official ATS/JRS/ALAT Clinical Practice Guideline. Am J Respir Crit Care Med. 2020;202(3):e36-e69. DOI: 10.1164/rccm.202005-2032ST. Erratum in: Am J Respir Crit Care Med. 2021;203(1):150-151. PMID: 32706311; PMCID: PMC7397797.</mixed-citation><mixed-citation xml:lang="en">Raghu G, Remy-Jardin M, Ryerson CJ, Myers JL et al. Diagnosis of Hypersensitivity Pneumonitis in Adults. An Official ATS/JRS/ALAT Clinical Practice Guideline. Am J Respir Crit Care Med. 2020 Aug 1; 202(3): e36-e69. doi: 10.1164/rccm.202005-2032ST.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Vasakova M, Morell F, Walsh S, Leslie K, Raghu G. Hypersensitivity Pneumonitis: Perspectives in Diagnosis and Management. Am J Respir Crit Care Med. 2017;196(6):680-689. DOI: 10.1164/rccm.201611-2201PP.</mixed-citation><mixed-citation xml:lang="en">Vasakova M., Morell F., Walsh S. et al. Hypersensitivity pneumonitis: perspectives in di-agnosis and management. Am. J. Respir. Crit. Care Med. 2017; 196 (6): 680–689. DOI: 10.1164/rccm.201611-2201PP.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Spagnolo P, Rossi G, Cavazza A, Bonifazi M, Paladini I, Bonella F, et al. Hypersensitivity Pneumonitis: A Comprehensive Review. J Investig Allergol Clin Immunol. 2015;25(4):237-50; quiz follow 250. PMID: 26310038.</mixed-citation><mixed-citation xml:lang="en">Spagnolo P., Rossi G., Cavazza A., Bonifazi M. et al. Hypersensitivity pneumonitis: a comprehensive review. J Investig. Allergol. Clin. Immunol. 2015;25(4):237–250.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ando A, Hagiya H, Nada T, Kimura K, Waseda K, Rai K, et al. Hypersensitivity Pneumonitis Caused by a Home Ultrasonic Humidifier Contaminated with Candida guilliermondii. Intern Med. 2017;56(22):3109-3112. DOI: 10.2169/internalmedicine.9055-17.</mixed-citation><mixed-citation xml:lang="en">Ando A, Hagiya H, Nada T, Kimura K et al. Hypersensitivity Pneumonitis Caused by a Home Ultrasonic Humidifier Contaminated with Candida guilliermondii. Intern Med. 2017 Nov 15;56(22):3109-3112. doi: 10.2169/internalmedicine.9055-17.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Utsugi H, Usui Y, Nishihara F, Kanazawa M, Nagata M. Mycobacterium gordonae-induced humidifier lung. BMC Pulm Med. 2015;15:108. DOI: 10.1186/s12890-0150107-y.</mixed-citation><mixed-citation xml:lang="en">Utsugi H, Usui Y, Nishihara F, Kanazawa M, Nagata M. Mycobacterium gordonae-induced humidifier lung. BMC Pulm Med. 2015 Sep 30;15:108. doi: 10.1186/s12890-015-0107-y.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Sakamoto S, Furukawa M, Shimizu H, Sekiya M, Miyoshi S, Nakamura Y, et al. Clinical and radiological characteristics of ultrasonic humidifier lung and summer-type hypersensitivity pneumonitis. Respir Med. 2020;174:106196. DOI: 10.1016/j.Rmed.2020.106196.</mixed-citation><mixed-citation xml:lang="en">Sakamoto S, Furukawa M, Shimizu H, Sekiya M. et al. Clinical and radiological charac-teristics of ultrasonic humidifier lung and summer‐type hypersensitivity pneumonitis. Respir. Med. 2020; 174: 106196. DOI: 10.1016/j.rmed.2020.106196.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
