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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">therapeutic</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский журнал терапевтической практики</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Therapeutic Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8156</issn><issn pub-type="epub">3033-8344</issn><publisher><publisher-name>РостГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2712-8156-2022-3-1-15-19</article-id><article-id custom-type="elpub" pub-id-type="custom">therapeutic-197</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Поражение сердца у больных с ревматоидным артритом</article-title><trans-title-group xml:lang="en"><trans-title>Heart damage in patients with rheumatoid arthritis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3463-7734</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ребров</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Rebrov</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ребров Андрей Петрович – доктор медицинских наук, профессор, заведующий кафедрой госпитальной терапии лечебного факультета.</p><p>Саратов.</p></bio><bio xml:lang="en"><p>Andrey P. Rebrov - Dr. Sci. (Med.), professor, head of the chair of hospital therapy of general medicine Department, V.I. Razumovskyy Saratov State Medical University.</p><p>Saratov.</p></bio><email xlink:type="simple">aprebrov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Саратовский государственный медицинский университет им. В.И. Разумовского Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.I. Razumovskyy Saratov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>16</day><month>03</month><year>2022</year></pub-date><volume>3</volume><issue>1</issue><fpage>15</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ребров А.П., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Ребров А.П.</copyright-holder><copyright-holder xml:lang="en">Rebrov A.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therapeutic-j.ru/jour/article/view/197">https://www.therapeutic-j.ru/jour/article/view/197</self-uri><abstract><p>В статье представлены данные о поражении сердца у пациентов с ревматоидным артритом (РА), особенностях развития ишемической и неишемической болезни сердца с существенным повышением риска неблагоприятных сердечно-сосудистых событий. Для пациентов с РА характерно повышение риска развития инфаркта миокарда, сердечной недостаточности, нарушений ритма, внезапной сердечной смерти и общей сердечно-сосудистой смерти. Подчёркивается возможность достаточно быстрого развития дисфункции миокарда у пациентов с РА с момента манифестации заболевания, развития и прогрессирования атеросклероза коронарных артерий, а при развитии у больных РА поражения коронарных артерий установлена худшая выживаемость после перенесенного инфаркта миокарда.</p><p>Имеющиеся факты позволяют говорить о ревматоидном артрите как о заболевании, вносящем существенный вклад в сердечно-сосудистую заболеваемость и смертность.</p></abstract><trans-abstract xml:lang="en"><p>The article presents data on heart damage in patients with rheumatoid arthritis (RA), features of the development of ischemic and non-ischemic heart disease with a significant increase in the risk of adverse cardiovascular events. Patients with RA are characterized by an increased risk of developing myocardial infarction, heart failure, rhythm disturbances, sudden cardiac death, and general cardiovascular death. The possibility of a fairly rapid development of myocardial dysfunction in patients with RA from the moment of manifestation of the disease, the development and progression of atherosclerosis of the coronary arteries is emphasized, and with the development of coronary artery disease in RA patients, the worst survival rate after a heart attack was established. The available evidence suggests that rheumatoid arthritis is a disease that makes a significant contribution to cardiovascular morbidity and mortality.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ревматоидный артрит</kwd><kwd>сердце</kwd><kwd>миокард</kwd><kwd>сердечно-сосудистая заболеваемость и смертность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rheumatoid arthritis</kwd><kwd>heart</kwd><kwd>myocardium</kwd><kwd>cardiovascular morbidity and mortality</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Avina-Zubieta JA, Thomas J, Sadatsafavi M, Lehman AJ, Lacaille D. Risk of incident cardiovascular events in patients with rheumatoid arthritis: a meta-analysis of observational studies. Ann Rheum Dis. 2012;71(9):1524-9. 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