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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">therapeutic</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский журнал терапевтической практики</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Therapeutic Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8156</issn><issn pub-type="epub">3033-8344</issn><publisher><publisher-name>РостГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2712-8156-2022-3-2-25-31</article-id><article-id custom-type="elpub" pub-id-type="custom">therapeutic-198</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Боль, нестероидные противовоспалительные препараты и хроническая болезнь почек: непростые взаимоотношения</article-title><trans-title-group xml:lang="en"><trans-title>Pain, nsaids, and chronic kidney disease: a diﬃcult relationship</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3463-7734</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ребров</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Rebrov</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ребров Андрей Петрович, д.м.н., проф., заведующий кафедрой госпитальной терапии лечебного факультета</p><p>Саратов</p></bio><bio xml:lang="en"><p>Andrey P. Rebrov, Dr. Sci. (Med.), professor, head of the chair of hospital therapy of general medicine Department</p><p>Saratov</p></bio><email xlink:type="simple">aprebrov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Саратовский государственный медицинский университет им. В. И. Разумовского» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V. I. Razumovskyy Saratov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>29</day><month>06</month><year>2022</year></pub-date><volume>3</volume><issue>2</issue><fpage>25</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ребров А.П., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Ребров А.П.</copyright-holder><copyright-holder xml:lang="en">Rebrov A.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therapeutic-j.ru/jour/article/view/198">https://www.therapeutic-j.ru/jour/article/view/198</self-uri><abstract><p> В статье представлены данные о частоте встречаемости болевого синдрома у пациентов с хронической болезнью почек разных стадий и о частоте применения пациентами нестероидных противовоспалительных препаратов (НПВП) для купирования боли, изложены основные причины развития острой и хронической боли. Представлены итоги обсуждения возможных рисков неблагоприятного влияния НПВП на состояние почек. Нередко пациенты не знают о наличии у них ХБП и принимают НПВП самостоятельно, а врачи недооценивают состояние почек при назначении препаратов для купирования боли.</p></abstract><trans-abstract xml:lang="en"><p>The article presents data on the incidence of pain in patients with chronic kidney disease of various stages, the main causes of acute and chronic pain, the frequency of use of non-steroidal anti-inﬂammatory drugs (NSAIDs) by patients for pain relief. The article discusses the possible risks of an adverse eﬀect of NSAIDs on kidney health. Unfortunately, often patients do not know about their CKD and take NSAIDs on their own, and doctors underestimate the condition of the kidneys when prescribing drugs to relieve pain.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>боль</kwd><kwd>нестероидные противовоспалительные препараты</kwd><kwd>хроническая болезнь почек</kwd><kwd>хроническая почечная недостаточность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pain</kwd><kwd>NSAIDs</kwd><kwd>chronic kidney disease</kwd><kwd>chronic renal failure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Nahin RL. Estimates of pain prevalence and severity in adults: United States, 2012. J Pain. 2015;16(8):769-80. DOI: 10.1016/j.jpain.2015.05.002</mixed-citation><mixed-citation xml:lang="en">Nahin RL. Estimates of pain prevalence and severity in adults: United States, 2012. J Pain. 2015;16(8):769-80. 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