therapeuticЮжно-Российский журнал терапевтической практикиSouth Russian Journal of Therapeutic Practice2712-81563033-8344РостГМУ10.21886/2712-8156-2022-3-3-17-24therapeutic-236Research ArticleОБЗОРЫREVIEWSCOVID-19 и нарушения сердечного ритма – есть ли связь?COVID-19 and arrhythmias - is there a relationship?https://orcid.org/0000-0002-7603-8481АхмедовВ. А.AkhmedovV. A.

Ахмедов Вадим Адильевич, доктор медицинских наук, проф., заведующий кафедрой медицинской реабилитации Дополнительного профессионального образования

Омск

Vadim A. Akhmedov, Dr. Sci. (Med.), Professor, Head of the Department of Medical Rehabilitation of Additional Professional Education

Omsk

v_akhmedov@mail.ruhttps://orcid.org/0000-0002-6581-7017ЛивзанМ. А.LivzanM. A.

Ливзан Мария Анатольевна, доктор медицинских наук, профессор, ректор, заведующая кафедрой факультетской терапии, гастроэнтерологии

Омск

 

Maria A. Livzan, Dr. Sci. (Med.), Professor, Rector, Head of the Department of Faculty Therapy, Gastroenterology

Omsk

mlivzan@yandex.ruhttps://orcid.org/0000-0001-9370-4768ГаусО. В.GausO. V.

Гаус Ольга Владимировна, кандидат медицинских наук, доцент кафедры факультетской терапии, гастроэнтерологии

Омск

Olga V. Gaus, Cand. Sci. (Med.), Associate Professor of the Department of Faculty Therapy, Gastroenterology

Omsk

gaus_olga@bk.ruФГБОУ ВО «Омский государственный медицинский университет» Минздрава РоссииРоссияOmsk State Medical UniversityRussian Federation202201092022331724Copyright © Ахмедов В.А., Ливзан М.А., Гаус О.В., 20222022Ахмедов В.А., Ливзан М.А., Гаус О.В.Akhmedov V.A., Livzan M.A., Gaus O.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.therapeutic-j.ru/jour/article/view/236

Инфекция COVID-19 связана со многими различными системными осложнениями. Среди них особенно важны осложнения со стороны сердечно-сосудистой системы, поскольку они связаны со значительной смертностью. Существует множество различных подгрупп сердечно-сосудистых осложнений, одной из которых являются аритмии. Аритмии имеют особое значение, поскольку у значительного процента пациентов аритмии возникают после заражения SARS-CoV-2 и у этих пациентов наблюдается повышенный уровень смертности. Аритмии у пациентов с COVID-19 связаны с воспалением, нарушениями электролитного баланса, гипоксией, ишемией миокарда, цитокинами, приемом проаритмических препаратов или препаратов, удлиняющих интервал QT, и сопутствующими заболеваниями, такими как тяжелая застойная сердечная недостаточность, наследственные синдромы аритмии или врождённые пороки сердца. Кроме того, аритмии и остановки сердца наиболее распространены среди тяжелобольных пациентов с COVID-19, находящихся в отделении интенсивной терапии. В представленной обзорной статье из публикаций PubMed/MedLined освещены связи между COVID-19 и аритмиями с подробным описанием возможных патофизиологических механизмов, существующих представлений о проаритмических факторах у взрослых пациентов с COVID-19.

COVID-19 infection is associated with many different systemic complications. Among these, cardiovascular system complications are particularly important as these are associated with significant mortality. There are many different subgroups of cardiovascular complications, with arrhythmias being one of them. Arrhythmias are especially important as there are a substantial percentage of patients who have arrhythmia after a COVID-19 infection, and these patients are seen with an increased mortality rate. Arrhythmias in COVID-19 patients are associated with inflammation, electrolyte abnormalities, hypoxia, myocardial ischemia, cytokines, pro-arrhythmic or QT-prolonging medications, and underlying heart conditions such as severe congestive heart failure, inherited arrhythmia syndromes, or congenital heart conditions. In addition, arrhythmias and cardiac arrests are most prevalent in the critically ill intensive care unit COVID-19 patient population. This review of PubMed/MedLine articled presents an overview of the association between COVID-19 and arrhythmias by detailing possible pathophysiological mechanisms, existing knowledge of pro-arrhythmic factors, and results from studies in adult COVID-19 populations.

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The authors declare that there are no conflicts of interest present.