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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">therapeutic</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский журнал терапевтической практики</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Therapeutic Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8156</issn><issn pub-type="epub">3033-8344</issn><publisher><publisher-name>РостГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2712-8156-2022-3-2-7-18</article-id><article-id custom-type="elpub" pub-id-type="custom">therapeutic-247</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Влияние метаболических нару шений на формирование патологии почек</article-title><trans-title-group xml:lang="en"><trans-title>Inﬂuence of metabolic disorders on the development of renal pathology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9344-1304</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Башкинов</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bashkinov</surname><given-names>R. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Башкинов Роман Андреевич, Медицинский советник «Евразийской Ассоциации Терапевтов», Москва; аспирант кафедры терапии, ревматологии, экспертизы временной нетрудоспособности и качества медицинской помощи им. Э. Э. Эйхвальда ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И. И. Мечникова», Санкт-Петербург</p></bio><bio xml:lang="en"><p>Roman A. Bashkinov, Medical advisor of the «Eurasian Association of Therapists», Moscow; postgraduate of the Department of therapy, rheumatology, examination of temporary disability and quality of medical care n. a. E. E. Eichwald, «North-Western State Medical University n. a. I. I. Mechnikov», Saint-Petersburg</p></bio><email xlink:type="simple">bashkinov-roman@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0210-2321</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Батлук</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Batluk</surname><given-names>T. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Батлук Татьяна Ивановна, к.м.н., ассистент кафедры пропедевтики внутренних болезней педиатрического факультета ФГАОУ ВО «РНИМУ им. Н. И. Пирогова» Минздрава России; медицинский советник «Евразийской Ассоциации Терапевтов»</p><p>Москва</p></bio><bio xml:lang="en"><p>Tatiana I. Batluk, PhD, Assistant of Department of Internal Medicine Propaedeutics of the Pediatric Faculty, «Pirogov Russian National Research Medical University»; medical advisor of the «Eurasian Association of Therapists»</p><p>Moscow</p></bio><email xlink:type="simple">tatianabatluk92@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8521-6542</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельников</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Melnikov</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мельников Евгений Сергеевич, медицинский советник «Евразийской Ассоциации Терапевтов», Москва; аспирант кафедры терапии, ревматологии, экспертизы временной нетрудоспособности и качества медицинской помощи им. Э. Э. Эйхвальда ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И. И. Мечникова», Санкт-Петербург</p></bio><bio xml:lang="en"><p>Evgeny S. Melnikov, Medical advisor of the «Eurasian Association of Therapists», Moscow; postgraduate of the Department of therapy, rheumatology, examination of temporary disability and quality of medical care n. a. E. E. Eichwald, «North-Western State Medical University n. a. I. I. Mechnikov», Saint-Petersburg</p></bio><email xlink:type="simple">melnikovzhenya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4116-096X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трубникова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Trubnikova</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трубникова Марина Александровна, медицинский советник «Евразийской Ассоциации Терапевтов», Москва; врач-нефролог ООО «Фрезениус Медиал Кеа Кубань», Сочи</p></bio><bio xml:lang="en"><p>Marina A. Trubnikova, Medical advisor of the «Eurasian Association of Therapists», Moscow; nephrologist of LLC «Fresenius Medical Care Kuban», Sochi</p></bio><email xlink:type="simple">mtrubnikova@euat.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1180-3549</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арутюнов</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Arutyunov</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Арутюнов Александр Григорьевич, д.м.н., вице-президент</p><p>Москва</p></bio><bio xml:lang="en"><p>Alexander G. Arutyunov, MD, Vice President</p><p>Moscow</p></bio><email xlink:type="simple">agarutyunov@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>«Евразийская Ассоциация Терапевтов»; ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И. И. Мечникова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>«Eurasian Association of Therapists»; «North-Western State Medical University n. a. I. I. Mechnikov»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>«Евразийская Ассоциация Терапевтов»; ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н. И. Пирогова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>«Eurasian Association of Therapists»; «Pirogov Russian National Research Medical University»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>«Евразийская Ассоциация Терапевтов»; ООО «Фрезениус Медиал Кеа Кубань»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>«Eurasian Association of Therapists»; LLC «Fresenius Medical Care Kuban»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>«Евразийская Ассоциация Терапевтов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>«Eurasian Association of Therapists»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>18</day><month>06</month><year>2022</year></pub-date><volume>3</volume><issue>2</issue><fpage>7</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Башкинов Р.А., Батлук Т.И., Мельников Е.С., Трубникова М.А., Арутюнов А.Г., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Башкинов Р.А., Батлук Т.И., Мельников Е.С., Трубникова М.А., Арутюнов А.Г.</copyright-holder><copyright-holder xml:lang="en">Bashkinov R.A., Batluk T.I., Melnikov E.S., Trubnikova M.A., Arutyunov A.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therapeutic-j.ru/jour/article/view/247">https://www.therapeutic-j.ru/jour/article/view/247</self-uri><abstract><p>Большой вклад в развитие патологии почек, в том числе и в прогрессирование хронической болезни почек, вносят факторы риска, связанные с нарушением метаболических процессов. К ним относятся нарушения углеводного обмена (предиабет, сахарный диабет), дислипидемии, избыточная масса тела, ожирение, метаболический синдром, гиперурикемия. Своевременное выявление этих факторов и их коррекция могут иметь решающее значения для пациента в контексте почечного повреждения. В обзоре представлены данные о влиянии нарушений углеводного, липидного и пуринового обменов, избыточной массы тела и ожирения на формирование патологии почек.</p></abstract><trans-abstract xml:lang="en"><p>A large contribution to the development of kidney pathology, including the progression of chronic kidney disease, is made by risk factors associated, among other things, with impaired metabolic processes. These include disorders of carbohydrate metabolism (prediabetes, diabetes mellitus), dyslipidemia, overweight, obesity, metabolic syndrome, hyperuricemia. Timely identiﬁcation of these factors and their correction can be crucial for the patient in the context of kidney damage. The review presents data on the impact of disorders of carbohydrate, lipid and purine metabolism, overweight and obesity on the formation of kidney pathology.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая болезнь почек</kwd><kwd>избыточная масса тела</kwd><kwd>гиперурикемия</kwd><kwd>дислипидемия</kwd><kwd>предиабет</kwd><kwd>сахарный диабет</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic kidney disease</kwd><kwd>overweight</kwd><kwd>hyperuricemia</kwd><kwd>dyslipidemia</kwd><kwd>prediabetes</kwd><kwd>diabetes mellitus</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации. Хроническая болезнь почек (ХБП). Нефрология. 2021;25(5):10-82.</mixed-citation><mixed-citation xml:lang="en">Клинические рекомендации. Хроническая болезнь почек (ХБП). 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