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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">therapeutic</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский журнал терапевтической практики</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Therapeutic Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8156</issn><issn pub-type="epub">3033-8344</issn><publisher><publisher-name>РостГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2712-8156-2023-4-2-18-24</article-id><article-id custom-type="elpub" pub-id-type="custom">therapeutic-361</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Остеоартрит и сердечно-сосудистые заболевания: непростые взаимоотношения</article-title><trans-title-group xml:lang="en"><trans-title>Osteoarthritis and cardiovascular disease: a complicated  relationship</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3463-7734</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ребров</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Rebrov</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ребров Андрей Петрович – доктор медицинских наук, профессор, профессор кафедры госпитальной терапии лечебного факультета.</p><p>Саратов</p></bio><bio xml:lang="en"><p>Andrey P. Rebrov - MD, professor, professor of hospital therapy of general medicine Department, V.I. Razumovsky Saratov State Medical University.</p><p>Saratov</p></bio><email xlink:type="simple">aprebrov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Саратовский государственный медицинский университет им. В.И. Разумовского» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.I. Razumovsky Saratov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>12</day><month>06</month><year>2023</year></pub-date><volume>4</volume><issue>2</issue><fpage>18</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ребров А.П., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Ребров А.П.</copyright-holder><copyright-holder xml:lang="en">Rebrov A.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therapeutic-j.ru/jour/article/view/361">https://www.therapeutic-j.ru/jour/article/view/361</self-uri><abstract><p>В статье представлены данные о частоте сочетания остеоартрита  и сердечно-сосудистых  заболеваний, особенностях  их взаимоотношений,  возможном влиянии препаратов,  применяемых при лечении сердечно-сосудистых заболеваний, на развитие и прогрессирование остеоартрита.</p></abstract><trans-abstract xml:lang="en"><p>The article presents data on the frequency of the combination of osteoarthritis and cardiovascular diseases, the features of their relationship, the possible impact of cardiovascular diseases and ongoing therapy on the development and progression of osteoarthritis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>остеоартрит</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>смертность</kwd><kwd>боль</kwd><kwd>суставной хрящ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>osteoarthritis</kwd><kwd>cardiovascular disease</kwd><kwd>mortality</kwd><kwd>pain</kwd><kwd>articular cartilage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Constantino de Campos G, Mundi R, Whittington C, Toutounji MJ, Ngai W, Sheehan B. 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