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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">therapeutic</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский журнал терапевтической практики</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Therapeutic Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8156</issn><publisher><publisher-name>РостГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2712-8156-2024-5-1-23-31</article-id><article-id custom-type="elpub" pub-id-type="custom">therapeutic-489</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Нарушения мочеиспускания при рассеянном склерозе</article-title><trans-title-group xml:lang="en"><trans-title>Urinary dysfunction in multiple sclerosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-0252-2752</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдуллах</surname><given-names>Немер М.Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdallax</surname><given-names>Nemer M.N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Абдуллах Немер М.Н., аспирант кафедры урологии и репродуктивного здоровья человека (с курсом детской урологии-андрологии)</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Abdallax Nemer M.N., postgraduate student (PhD) of the Department of Urology and Human Reproductive Health (with a course of pediatric Urology-Andrology)</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">n_m2015@live.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0674-9429</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белоусов</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Belousov</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белоусов Игорь Иванович, д.м.н., доцент, профессор кафедры урологии и репродуктивного здоровья человека (с курсом детской урологии-андрологии)</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Belousov Igor I., Dr. Sci. (Med.), Professor of the Department of Urology and Human Reproductive Health (with a course of pediatric Urology-Andrology)</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">belrost_dept@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7093-9548</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гончарова</surname><given-names>З. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Goncharova</surname><given-names>Z. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гончарова Зоя Александровна, д.м.н., доцент, профессор кафедры нервных болезней и нейрохирургии, ФГБОУ ВО «Ростовский государственный медицинский университет» Минздрава России, заведующая центром неврологическим Клиники ФГБОУ ВО РостГМУ Минздрава России</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Goncharova Zoya A., Dr. Sci. (Med.), Professor of the Department of Nervous Diseases and Neurosurgery, Rostov State Medical University, Head of the Neurological Center of the Clinic of the Rostov State Medical University</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">centrms@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1958-9858</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исмаилов</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ismailov</surname><given-names>R. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Исмаилов Руслан Самедович, к.м.н, ассистент кафедры урологии и репродуктивного здоровья человека (с курсом детской урологии-андрологии)</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Ismailov Ruslan S., Cand. Sci. (Med.), assistant of the Department of Urology and Human Reproductive Health (with a course of pediatric Urology-Andrology)</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">dr.ruslan.ismailov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-0220-1656</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Руденко</surname><given-names>О. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Rudenko</surname><given-names>O. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Руденко Ольга Юрьевна, к.м.н., ассистент кафедры нервных болезней и нейрохирургии</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Rudenko Olga Yu., Cand. Sci. (Med.), assistant of the Department of Nervous Diseases and Neurosurgery</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">olyt@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-0103-0412</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пчелкин</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pchelkin</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пчелкин Артем Сергеевич, студент 6 курса лечебно-профилактического факультета</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Pchelkin Artem S., 6th year student, Faculty of General Medicine</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">pchelkin131@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБОУ ВО «Ростовский государственный медицинский университет» Минздрава России<country>Россия</country></aff><aff xml:lang="en">Rostov State Medical University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>29</day><month>03</month><year>2024</year></pub-date><volume>5</volume><issue>1</issue><fpage>23</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Абдуллах Н.М., Белоусов И.И., Гончарова З.А., Исмаилов Р.С., Руденко О.Ю., Пчелкин А.С., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Абдуллах Н.М., Белоусов И.И., Гончарова З.А., Исмаилов Р.С., Руденко О.Ю., Пчелкин А.С.</copyright-holder><copyright-holder xml:lang="en">Abdallax N.M., Belousov I.I., Goncharova Z.A., Ismailov R.S., Rudenko O.Y., Pchelkin A.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therapeutic-j.ru/jour/article/view/489">https://www.therapeutic-j.ru/jour/article/view/489</self-uri><abstract><p>В настоящем обзоре представлена актуальность обязательной оценки функции нижних мочевых путей при рассеянном склерозе для выявления симптомов со стороны нижних мочевых путей, характера и выраженности инвалидизации пациентов относительно нарушений мочеиспускания. Симптомы нижних мочевых путей при рассеянном склерозе многообразны и соотносятся с фазами миктурического цикла. Нарушения акта мочеиспускания при рассеянном склерозе наиболее часто представлены императивными позывами к мочеиспусканию или спорадическими эпизодами задержки мочеиспускания. При прогрессировании заболевания наряду с императивностью и сенсорными нарушениями формируется недержание мочи, результирующее до тотального недержания мочи в наиболее тяжёлых случаях. Также может формироваться хроническая ретенция мочи, что определяет необходимость отведения мочи из мочевого пузыря посредством уретрального дренирования. В свою очередь существенно повышается риск развития инфекции мочевых путей, в том числе катетер-ассоциированной.</p></abstract><trans-abstract xml:lang="en"><p>This review presents the relevance of mandatory assessment of the function of the lower urinary tract in multiple sclerosis to identify the lower urinary tract symptoms, the nature and severity of disability in patients regarding urinary disorders. Lower urinary tract symptoms in multiple sclerosis are diverse and correlate with the phases of the urination cycle. lower urinary tract symptoms in multiple sclerosis include urinary urgency or sporadic episodes of urinary retention. As the disease progresses, along with urgency and sensory disturbances, urinary incontinence develops, resulting in total urinary incontinence in the most severe cases. Chronic urine retention may also form, which determines the need to urine diversion from the bladder through urethral drainage. In turn, the risk of developing urinary tract infections, including catheter-associated ones, increases significantly.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рассеянный склероз</kwd><kwd>нарушения мочеиспускания</kwd><kwd>симптомы нижних мочевых путей</kwd><kwd>нейрогенная дисфункция нижних мочевых путей</kwd></kwd-group><kwd-group xml:lang="en"><kwd>multiple sclerosis</kwd><kwd>urinary disorders</kwd><kwd>lower urinary tract symptoms</kwd><kwd>neurogenic dysfunction of the lower urinary tract</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Montalban X, Gold R, Thompson AJ, Otero-Romero S, Amato MP, Chandraratna D, et al. ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis. Eur J Neurol. 2018;25(2):215-237. Erratum in: Eur J Neurol. 2018;25(3):605. PMID: 29352526. 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