therapeuticЮжно-Российский журнал терапевтической практикиSouth Russian Journal of Therapeutic Practice2712-81563033-8344РостГМУ10.21886/2712-8156-2024-5-4-15-22therapeutic-557Research ArticleОБЗОРЫREVIEWSАтеросклероз периферических артерий и сердечная недостаточность: обзор современного состояния проблемыPeripheral arterial atherosclerosis and heart failure: state of the art reviewhttps://orcid.org/0000-0001-5902-3803ГенкельВ. В.GenkelV. V.

Генкель Вадим Викторович, к.м.н., доцент кафедры Пропедевтики внутренних болезней

Челябинск

Vadim V. Genkel, Cand. Sci. (Med.), Associate Professor of Department of Propedeutics of Internal Medicine

Chelyabinsk

henkel-07@mail.ruhttps://orcid.org/0009-0006-0775-6355ЛатышеваО. В.LatyshevaO. V.

Латышева Олеся Владимировна, главный врач

Агаповка

Olesya V. Latysheva, chief physician

Agapovka

cynara84@mail.ruhttps://orcid.org/0009-0008-6190-8940ЕршовС. В.ErshovS. V.

Ершов Сергей Владимирович, врач-реаниматолог

Челябинск

Sergey V. Ershov, intensive care physician

Chelyabinsk

sergei.eee-ershov@yandex.ruhttps://orcid.org/0000-0002-7954-2990ЛебедевЕ. В.LebedevE. V.

Лебедев Евгений Владимирович, к.м.н., доцент кафедры Пропедевтики внутренних болезней

Челябинск

Evgeny V. Lebedev, Cand. Sci. (Med.), Associate Professor of Department of Propedeutics of Internal Medicine

Chelyabinsk

evgueni.lebedev@mail.ruhttps://orcid.org/0000-0002-1136-7284КузнецоваА. С.KuznetsovaA. S.

Кузнецова Алла Сергеевна, к.м.н., доцент кафедры Госпитальной терапии

Челябинск

Alla S. Kuznetsova, Cand. Sci. (Med.), Associate Professor of Department of Hospital therapy

Chelyabinsk

kuzja321@mail.ruhttps://orcid.org/0000-0003-3962-3662СалашенкоА. О.SalashenkoA. O.

Салашенко Алексей Олегович, к.м.н., доцент кафедры Пропедевтики внутренних болезней

Челябинск

Alexey O. Salashenko, Cand. Sci. (Med.), Associate Professor of Department of Propedeutics of Internal Medicine

Chelyabinsk

salachenko@hotmail.comhttps://orcid.org/0000-0002-7731-7730ШапошникИ. И.ShaposhnikI. I.

Шапошник Игорь Иосифович, д.м.н., профессор, заведующий кафедрой Пропедевтики внутренних болезней

Челябинск

Igor I. Shaposhnik, Dr. Sci. (Med.), Professor, Head of Department of Propedeutics of Internal Medicine

Chelyabinsk

shaposhnik@yandex.ruФГБОУ ВО «Южно-Уральский государственный медицинский университет» Минздрава РоссииРоссияSouth-Ural State Medical UniversityRussian FederationГБУЗ «Районная больница с. Агаповка»РоссияRural hospital of AgapovkaRussian FederationГАУЗ ОТКЗ «Городская клиническая больница № 1 г. Челябинск»РоссияChelyabinsk City Clinical Hospital №1Russian Federation202426112024541522Copyright © Генкель В.В., Латышева О.В., Ершов С.В., Лебедев Е.В., Кузнецова А.С., Салашенко А.О., Шапошник И.И., 20242024Генкель В.В., Латышева О.В., Ершов С.В., Лебедев Е.В., Кузнецова А.С., Салашенко А.О., Шапошник И.И.Genkel V.V., Latysheva O.V., Ershov S.V., Lebedev E.V., Kuznetsova A.S., Salashenko A.O., Shaposhnik I.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.therapeutic-j.ru/jour/article/view/557

Сердечная недостаточность рассматривается как терминальный этап кардиоваскулярного континуума, начинающегося с экспозиции факторами риска с последующим развитием бессимптомного поражения сердечно-сосудистой системы, прогрессирующего до клинически манифестных заболеваний. Конвенциональные факторы риска, такие как артериальная гипертензия, дислипидемия, ожирение, сахарный диабет, с одной стороны напрямую обусловливают структурно-функциональное изменение сердца, с другой — способствуют развитию и прогрессированию атеросклероза. Несмотря на то, что мультифокальный характер атеросклероза является общеизвестным, данные исследований о роли атеросклероза периферических артерий в развитии сердечной недостаточности крайне ограничены. Изучение потенциальных взаимосвязей атеросклероза периферических артерий и сердечной недостаточности является актуальным во всех половозрастных группах пациентов.

Heart failure is considered as a terminal stage of the cardiovascular continuum, beginning with exposure to risk factors followed by the development of asymptomatic cardiovascular damage, progressing to clinically manifest disease. Conventional risk factors such as arterial hypertension, dyslipidemia, obesity, and diabetes mellitus, on the one hand, directly cause structural and functional changes in the heart, and on the other hand, contribute to the development and progression of atherosclerosis. Despite the fact that the multifocal nature of atherosclerosis is well known, research data on the role of peripheral arterial atherosclerosis in the development of heart failure are extremely limited. The study of potential relationships between atherosclerosis of peripheral arteries and heart failure is relevant in all sex and age groups of patients.

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The authors declare that there are no conflicts of interest present.