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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">therapeutic</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский журнал терапевтической практики</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Therapeutic Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8156</issn><issn pub-type="epub">3033-8344</issn><publisher><publisher-name>РостГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2712-8156-2024-5-4-119-124</article-id><article-id custom-type="elpub" pub-id-type="custom">therapeutic-570</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Синдром умеренных когнитивных расстройств при окклюзионно-стенотическом поражении брахиоцефальных артерии (анализ клинических наблюдений)</article-title><trans-title-group xml:lang="en"><trans-title>Syndrome of moderate cognitive disorders in occlusal-stenotica lesions of the brachiocephal arteries (analysis of clinical observations)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ковалева</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovaleva</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ковалева Наталия Сергеевна, к.м.н., доцент кафедры нервных болезней и нейрохирургии</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Natalia S. Kovaleva, Cand. Sci. (Med.), Associate Professor of the Department of Nervous Diseases and Neurosurgery</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">natrm@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-1946-2408</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Забазнов</surname><given-names>К. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Zabaznov</surname><given-names>K. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Забазнов Константин Г., к.м.н. доцент кафедры хирургический болезней №1</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Konstantin G. Zabaznov, Cand. Sci. (Med.)</p><p>Rostov-on-Don</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ростовский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>26</day><month>11</month><year>2024</year></pub-date><volume>5</volume><issue>4</issue><fpage>119</fpage><lpage>124</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ковалева Н.С., Забазнов К.Г., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Ковалева Н.С., Забазнов К.Г.</copyright-holder><copyright-holder xml:lang="en">Kovaleva N.S., Zabaznov K.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therapeutic-j.ru/jour/article/view/570">https://www.therapeutic-j.ru/jour/article/view/570</self-uri><abstract><p>В настоящей статье приведён анализ двух клинических наблюдений пациентов со стенотическим и окклюзионным атеросклеротическим поражением брахиоцефальных артерий в различных комбинациях. У обоих больных отмечались безынсультное течение и раннее формирование синдрома умеренных когнитивных расстройств. В ходе работы с пациентами был проведён тщательный анализ жалоб, анамнеза заболевания, клинико-нейропсихологическое обследование, выполнен расширенный объём исследований (общеклиническое, биохимическое, ультразвуковое, магнитно-резонансное, ангиографическое). На основании полученных данных установлен диагноз и проведено хирургическое лечение. Последующий развернутый неврологический осмотр, включавший в себя нейропсихологическое обследование, выявил повышение суммарного балла по монреальской шкале оценки когнитивных функций и позитивную тенденцию по показателям управляющих функций. Результаты анализа приведённых случаев подчеркивают важность раннего выявления и комплексного подхода к терапии для улучшения качества жизни пациентов и предотвращения дальнейшего прогрессирования когнитивного дефицита.</p></abstract><trans-abstract xml:lang="en"><p>This article analyzes two clinical observations of patients with stenotic and occlusive atherosclerotic lesions of the brachiocephalic arteries in various combinations. Both patients had a stroke-free course and early formation of the syndrome of moderate cognitive disorders. In the course of working with patients, a thorough analysis of complaints, anamnesis of the disease, clinical and neuropsychological examination was carried out, an expanded volume of studies was performed: general clinical, biochemical, ultrasound, magnetic resonance, angiographic. Based on the data obtained, a diagnosis was made and surgical treatment was performed. A subsequent detailed neurological examination, which included a neuropsychological examination, revealed an increase in the total score on the Montreal cognitive function assessment scale and a positive trend in indicators of control functions. The results of the analysis of these cases emphasize the importance of early detection and an integrated approach to therapy to improve the quality of life of patients and prevent further progression of cognitive deficits.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром умеренного когнитивного расстройства</kwd><kwd>когнитивные нарушения</kwd><kwd>сердечно-сосудистые факторы риска</kwd><kwd>стентирование брахиоцефальных артерий</kwd><kwd>окклюзия внутренней сонной артерии</kwd><kwd>стеноз внутренней сонной артерии</kwd><kwd>окклюзия позвоночной артерии</kwd><kwd>стеноз позвоночной артерии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>mild cognitive impairment syndrome</kwd><kwd>cognitive impairment</kwd><kwd>cardiovascular risk factors</kwd><kwd>brachiocephalic artery stenting</kwd><kwd>internal carotid artery occlusion</kwd><kwd>internal carotid artery stenosis</kwd><kwd>vertebral artery occlusion</kwd><kwd>vertebral artery stenosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Skvortsova V.I., Stakhovskaya L.V., Gudkova V.V., Alekhin A.V. 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