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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">therapeutic</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский журнал терапевтической практики</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Therapeutic Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8156</issn><publisher><publisher-name>РостГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2712-8156-2025-6-1-51-58</article-id><article-id custom-type="elpub" pub-id-type="custom">therapeutic-601</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Кардиометаболический профиль и показатели суточного мониторинга артериального давления у беременных с артериальной гипертензией белого халата</article-title><trans-title-group xml:lang="en"><trans-title>Cardiometabolic profile and 24-hour blood pressure monitoring parameters in pregnant women with white coat hypertension</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4958-4695</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николенко</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolenko</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Екатерина Сергеевна Николенко, ассистент</p><p>кафедра факультетской терапии</p><p>Челябинск</p></bio><bio xml:lang="en"><p>Ekaterina S. Nikolenko, Assistant Professor</p><p>Department of Faculty Therapy</p><p>Chelyabinsk</p></bio><email xlink:type="simple">nikolenkokate@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0952-6856</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чулков</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Chulkov</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Василий Сергеевич Чулков, д. м. н., доцент, профессор</p><p>кафедра внутренних болезней</p><p>Великий Новгород</p></bio><bio xml:lang="en"><p>Vasily S. Chulkov, Dr. Sci. (Med.), Associate Professor, Professor</p><p>Department of Internal Medicine</p><p>Veliky Novgorod</p></bio><email xlink:type="simple">vschulkov@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1948-8523</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чулков</surname><given-names>Вл. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Chulkov</surname><given-names>Vl. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владислав Сергеевич Чулков, к. м. н., доцент</p><p>кафедра факультетской терапии</p><p>Челябинск</p></bio><bio xml:lang="en"><p>Vladislav S. Chulkov, Cand. Sci. (Med.), Associate Professor</p><p>Department of Faculty Therapy</p><p>Chelyabinsk</p></bio><email xlink:type="simple">vlad.chulkov.1989@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБОУ ВО «Южно-Уральский государственный медицинский университет» Минздрава России<country>Россия</country></aff><aff xml:lang="en">South Ural State Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ФГБОУ ВО «Новгородский государственный университет им. Ярослава Мудрого»<country>Россия</country></aff><aff xml:lang="en">Yaroslav-the-Wise Novgorod State University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>07</day><month>02</month><year>2025</year></pub-date><volume>6</volume><issue>1</issue><fpage>51</fpage><lpage>58</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Николенко Е.С., Чулков В.С., Чулков В.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Николенко Е.С., Чулков В.С., Чулков В.С.</copyright-holder><copyright-holder xml:lang="en">Nikolenko E.S., Chulkov V.S., Chulkov V.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therapeutic-j.ru/jour/article/view/601">https://www.therapeutic-j.ru/jour/article/view/601</self-uri><abstract><sec><title>   Цель</title><p>   Цель: провести сравнительную оценку кардиометаболических показателей и параметров суточного мониторинга артериального давления (СМАД) у беременных с артериальной гипертензией (АГ) белого халата и с нормальным артериальным давлением.</p></sec><sec><title>   Материалы и методы</title><p>   Материалы и методы: в проспективное когортное исследование включены 88 беременных в возрасте 18–44 лет: I группа (основная) — 44 женщины с АГ белого халата (32 ± 5,7 лет), II группа (группа сравнения) — 44 женщины с нормальным артериальным давлением (28 ± 5,9 лет).</p></sec><sec><title>   Результаты</title><p>   Результаты: наиболее значимые различия в группах I и II были получены по уровням глюкозы, холестерина липопротеидов низкой плотности и мочевой кислоты в сыворотке крови. При оценке факторов кардиометаболического риска значимые различия были получены только по частоте абдоминального ожирения. Только у беременных с АГ белого халата встречалась преэклампсия и гестационная АГ в анамнезе. Среднее систолическое артериальное давление (САД) и диастолическое артериальное давление (ДАД) днем и ночью, вариабельность САД днём, индекс времени САД днем, индекс времени ДАД днем и ночью, средняя ЧСС днём, скорость утреннего подъёма САД и ДАД, а также большая частота нон-дипперов были достоверно выше у беременных в I группе по сравнению со II группой.</p></sec><sec><title>   Заключение</title><p>   Заключение: проведение суточного мониторинга артериального давления до 20 недель беременности позволяет не только распознать артериальную гипертензию белого халата, но и выделить группу риска по более тщательному наблюдению беременных с данным фенотипом АГ.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>   Objective</title><p>   Objective: to perform a comparative assessment of cardiometabolic parameters and 24-h blood pressure monitoring indicators in pregnant women with white-coat hypertension and normal blood pressure.</p></sec><sec><title>   Materials and methods</title><p>   Materials and methods: this prospective cohort study included 88 pregnant women aged 18–44 years: group 1 (study group) – 44 women with white coat hypertension (aged 32 ± 5.7 years); group 2 (comparison group) – 44 women with normal blood pressure (aged 28 ± 5.9 years).</p></sec><sec><title>   Results</title><p>   Results: the most significant differences between groups 1 and 2 were observed in serum glucose, low-density lipoprotein cholesterol, and uric acid. In assessing cardiometabolic risk factors, significant differences were found only in the frequency of abdominal obesity. Only pregnant women with white-coat hypertension had a history of preeclampsia and gestational hypertension. The mean daytime and nighttime systolic blood pressure (SBP) and diastolic blood pressure (DBP), daytime variability of SBP, daytime time index of SBP, daytime and nighttime time index of DBP, daytime mean heart rate, the rate of morning rise of SBP and DBP, as well as a high frequency of non-dippers were significantly higher in pregnant women in group 1 compared to group 2.</p></sec><sec><title>   Conclusion</title><p>   Conclusion: 24-h blood pressure monitoring up to 20 weeks of pregnancy allows not only recognition of white-coat hypertension but also identification of a high-risk group for more careful monitoring of pregnant women with this hypertension phenotype.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия белого халата</kwd><kwd>факторы кардиометаболического риска</kwd><kwd>суточный мониторинг артериального давления</kwd><kwd>беременность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>white coat hypertension (WCH)</kwd><kwd>cardiometabolic risk factors</kwd><kwd>24-h blood pressure monitoring</kwd><kwd>pregnancy</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Работа выполнена в рамках государственного задания «Прогнозирование и профилактика сердечно-сосудистого риска у лиц молодого возраста» 121040100269-6</funding-statement></funding-group><funding-group xml:lang="en"><funding-statement>The work was performed within the framework of the state task "Prediction and prevention of cardiovascular risk in young people" 121040100269-6</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Стрюк Р.И., Бунин Ю.А., Гурьева В.М., Иртюга О.Б., Коков Л.С., Коломацкая О.Е., и др. 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