<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">therapeutic</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский журнал терапевтической практики</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Therapeutic Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8156</issn><publisher><publisher-name>РостГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2712-8156-2025-6-1-7-10</article-id><article-id custom-type="elpub" pub-id-type="custom">therapeutic-604</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Гипертоническая болезнь у беременных с ожирением (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Hypertension in obese pregnant wome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-0858-6560</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Згуевич</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Zguevich</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ирина Михайловна Згуевич, аспирант</p><p>кафедра факультетской терапии</p><p>Красноярск</p></bio><bio xml:lang="en"><p>Irina M. Zguevich, postgraduate student</p><p>Department of Faculty Therapy</p><p>Krasnoyarsk</p></bio><email xlink:type="simple">tientos@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6968-7627</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никулина</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikulina</surname><given-names>S. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Светлана Юрьевна Никулина, д. м. н., проф., заведующая кафедрой</p><p>кафедра факультетской терапии</p><p>Красноярск</p></bio><bio xml:lang="en"><p>Svetlana Y. Nikulina, Dr. Sci. (Med.), Professor, Head of the Department</p><p>Department of Faculty Therapy</p><p>Krasnoyarsk</p></bio><email xlink:type="simple">nicoulina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2977-1792</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чернова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анна Александровна Чернова, д. м. н., проф., руководитель отдела</p><p>отдел науки и инновации</p><p>Красноярск</p></bio><bio xml:lang="en"><p>Anna A. Chernova, Dr. Sci. (Med.), Professor, Head of the Department</p><p>Department of Science and Innovation</p><p>Krasnoyarsk</p></bio><email xlink:type="simple">chernova-krsk@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБОУ ВО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России<country>Россия</country></aff><aff xml:lang="en">Krasnoyarsk State Medical University n. a. Professor V.F. Voino-Yasenetsky<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ФГБОУ ВО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России; ФГБУ «Федеральный Сибирский научно-клинический центр» ФМБА России<country>Россия</country></aff><aff xml:lang="en">Krasnoyarsk State Medical University n. a. Professor V.F. Voino-Yasenetsky; Federal Siberian Scientific and Clinical Center<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>07</day><month>03</month><year>2025</year></pub-date><volume>6</volume><issue>1</issue><fpage>7</fpage><lpage>10</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Згуевич И.М., Никулина С.Ю., Чернова А.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Згуевич И.М., Никулина С.Ю., Чернова А.А.</copyright-holder><copyright-holder xml:lang="en">Zguevich I.M., Nikulina S.Y., Chernova A.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therapeutic-j.ru/jour/article/view/604">https://www.therapeutic-j.ru/jour/article/view/604</self-uri><abstract><p>   Гипертоническая болезнь — это одно из наиболее распространённых заболеваний, особенно среди беременных женщин. Сочетание гипертонической болезни с ожирением представляет собой серьёзную проблему, требующую внимательного медицинского контроля. В данном обзоре литературы освещены вопросы влияние ожирения у беременных женщин в ассоциации с гипертонической болезнью на риски течения гестационного периода и неблагоприятных исходов беременности в рамках исследовательских работ российских и зарубежных авторов. Поиск публикаций на русском и английском языках осуществляли на базах данных и электронных ресурсах «PubMed» (MEDLIN), «Scopus», «eLIBRARY» по следующим ключевым словам: «беременность», «гипертоническая болезнь», «ожирение». В представленном обзоре литературы рассмотрены только статьи с полным текстом в открытом доступе. При подготовке обзора литературы проведен анализ публикаций с 2000 года. Дата последнего поиска — 27. 01. 2025. Всего были рассмотрены 19 статей.d.</p></abstract><trans-abstract xml:lang="en"><p>   Hypertension is one of the most common diseases, especially among pregnant women. The combination of hypertension and obesity is a serious problem that requires careful medical monitoring. This literature review highlights the impact of obesity in pregnant women in association with hypertension on the risks of the gestational period and adverse pregnancy outcomes, within the framework of research works by Russian and foreign authors. The search for publications in Russian and English was carried out on the databases and electronic resources PubMed (MEDLIN), Scopus, eLIBRARY using the following keywords: “pregnancy”, “hypertension”, “obesity”. The presented literature review only considers articles with full text in open access. In preparing the literature review, an analysis of publications since 2000 was carried out. Last search date: 01. 27. 2025. A total of 19 articles were reviewed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>обзор</kwd><kwd>беременность</kwd><kwd>гипертоническая болезнь</kwd><kwd>ожирение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>review</kwd><kwd>pregnancy</kwd><kwd>hypertension</kwd><kwd>obesity</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Исследование не имело спонсорской поддержки</funding-statement></funding-group><funding-group xml:lang="en"><funding-statement>The study had no sponsorship</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бичан Н.А., Рублевская А.С., Мальцева Н.В., Осокина В.Р., Черных Н.С. Изменения эндотелиальной NO-синтазы у беременных с хронической артериальной гипертонией и курением. Медицина в Кузбассе. 2021;(3):55-60. DOI: 10.24412/2687-0053-2021-3-55-60</mixed-citation><mixed-citation xml:lang="en">Bichan N.A., Rublevskaya A.S., Maltseva N.V., Osokina V.R., Chernykh N.S. Changes in endothelial NO synthase in pregnant women with chronic arterial hypertension and smoking. Medicine in Kuzbass. 2021.3:55-60. (In Russ.) DOI: 10.24412/2687-0053-2021-3-55-60</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Wagata M, Kogure M, Nakaya N, Tsuchiya N, Nakamura T, Hirata T, et al. Hypertensive disorders of pregnancy, obesity, and hypertension in later life by age group: a cross-sectional analysis. Hypertens Res. 2020;43(11):1277-1283. DOI: 10.1038/s41440-020-0463-8</mixed-citation><mixed-citation xml:lang="en">Wagata M, Kogure M, Nakaya N, Tsuchiya N, Nakamura T, Hirata T, et al. Hypertensive disorders of pregnancy, obesity, and hypertension in later life by age group: a cross-sectional analysis. Hypertens Res. 2020;43(11):1277-1283. DOI: 10.1038/s41440-020-0463-8</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Brombach C, Tong W, Giussani DA. Maternal obesity: new placental paradigms unfolded. Trends Mol Med. 2022;28(10):823-835. DOI: 10.1016/j.molmed.2022.05.013</mixed-citation><mixed-citation xml:lang="en">Brombach C, Tong W, Giussani DA. Maternal obesity: new placental paradigms unfolded. Trends Mol Med. 2022;28(10):823-835. DOI: 10.1016/j.molmed.2022.05.013</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Purohit A, Oyeka CP, Khan SS, Toscano M, Nayak S, Lawson SM, et al. Preventing Adverse Cardiovascular Outcomes in Pregnancy Complicated by Obesity. Curr Obstet Gynecol Rep. 2023;12(2):129-137. DOI: 10.1007/s13669-023-00356-9</mixed-citation><mixed-citation xml:lang="en">Purohit A, Oyeka CP, Khan SS, Toscano M, Nayak S, Lawson SM, et al. Preventing Adverse Cardiovascular Outcomes in Pregnancy Complicated by Obesity. Curr Obstet Gynecol Rep. 2023;12(2):129-137. DOI: 10.1007/s13669-023-00356-9</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Lewandowska M, Więckowska B, Sajdak S. Pre-Pregnancy Obesity, Excessive Gestational Weight Gain, and the Risk of Pregnancy-Induced Hypertension and Gestational Diabetes Mellitus. J Clin Med. 2020;9(6):1980. DOI: 10.3390/jcm9061980</mixed-citation><mixed-citation xml:lang="en">Lewandowska M, Więckowska B, Sajdak S. Pre-Pregnancy Obesity, Excessive Gestational Weight Gain, and the Risk of Pregnancy-Induced Hypertension and Gestational Diabetes Mellitus. J Clin Med. 2020;9(6):1980. DOI: 10.3390/jcm9061980</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Bartsch E, Medcalf KE, Park AL, Ray JG; High Risk of Pre-eclampsia Identification Group. Clinical risk factors for pre-eclampsia determined in early pregnancy : systematic review and meta-analysis of large cohort studies. BMJ. 2016;353:i1753. DOI: 10.1136/bmj.i1753</mixed-citation><mixed-citation xml:lang="en">Bartsch E, Medcalf KE, Park AL, Ray JG; High Risk of Pre-eclampsia Identification Group. Clinical risk factors for pre-eclampsia determined in early pregnancy : systematic review and meta-analysis of large cohort studies. BMJ. 2016;353:i1753. DOI: 10.1136/bmj.i1753</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Phipps EA, Thadhani R, Benzing T, Karumanchi SA. Author Correction: Pre-eclampsia: pathogenesis, novel diagnostics and therapies. Nat Rev Nephrol. 2019;15(6):386. Erratum for: Nat Rev Nephrol. 2019;15(5):275-289. DOI: 10.1038/s41581-019-0156-1.</mixed-citation><mixed-citation xml:lang="en">Phipps EA, Thadhani R, Benzing T, Karumanchi SA. Author Correction: Pre-eclampsia: pathogenesis, novel diagnostics and therapies. Nat Rev Nephrol. 2019;15(6):386. Erratum for: Nat Rev Nephrol. 2019;15(5):275-289. DOI: 10.1038/s41581-019-0156-1.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Olson KN, Redman LM, Sones JL. Obesity “complements” preeclampsia. Physiol Genomics. 2019;51(3):73-76. DOI: 10.1152/physiolgenomics.00102.2018</mixed-citation><mixed-citation xml:lang="en">Olson KN, Redman LM, Sones JL. Obesity “complements” preeclampsia. Physiol Genomics. 2019;51(3):73-76. DOI: 10.1152/physiolgenomics.00102.2018</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Young OM, Twedt R, Catov JM. Pre-pregnancy maternal obesity and the risk of preterm preeclampsia in the American primigravida. Obesity (Silver Spring). 2016;24(6):1226-1229. DOI: 10.1002/oby.21412</mixed-citation><mixed-citation xml:lang="en">Young OM, Twedt R, Catov JM. Pre-pregnancy maternal obesity and the risk of preterm preeclampsia in the American primigravida. Obesity (Silver Spring). 2016;24(6):1226-1229. DOI: 10.1002/oby.21412</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Patro Golab B, Santos S, Voerman E, Lawlor DA, Jaddoe VWV, Gaillard R; et al. Influence of maternal obesity on the association between common pregnancy complications and risk of childhood obesity: an individual participant data meta-analysis. Lancet Child Adolesc Health. 2018;2(11):812-821. DOI: 10.1016/S2352-4642(18)30273-6</mixed-citation><mixed-citation xml:lang="en">Patro Golab B, Santos S, Voerman E, Lawlor DA, Jaddoe VWV, Gaillard R; et al. Influence of maternal obesity on the association between common pregnancy complications and risk of childhood obesity: an individual participant data meta-analysis. Lancet Child Adolesc Health. 2018;2(11):812-821. DOI: 10.1016/S2352-4642(18)30273-6</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Диагностика и лечение сердечно-сосудистых заболеваний при беременности 2018. Национальные рекомендации. Российский кардиологический журнал. 2018;(3):91-134. DOI: 10.15829/1560-4071-2018-3-91-134</mixed-citation><mixed-citation xml:lang="en">Diagnosis and treatment of cardiovascular diseases during pregnancy 2018. National guidelines. Russian Journal of Cardiology. 2018;(3):91-134. (In Russ.) DOI: 10.15829/1560-4071-2018-3-91-134</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Бичан Н.А., Рублевская А.С. Роль курения в развитии артериальной гипертонии у беременных. Байкальский медицинский журнал. 2023;2(3):32-33. DOI: 10.57256/2949-0715-2023-3-32-33 – Bichan N.A., Rublevskaya A.S. The role of smoking in the development of arterial hypertension in pregnant women. Baikal Medical Journal. 2023;2(3):32-33. (In Russ.) DOI: 10.57256/2949-0715-2023-3-32-33</mixed-citation><mixed-citation xml:lang="en">Bichan N.A., Rublevskaya A.S. The role of smoking in the development of arterial hypertension in pregnant women. Baikal Medical Journal. 2023;2(3):32-33. (In Russ.) DOI: 10.57256/2949-0715-2023-3-32-33</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Adwani N, Fouly H, Omer T. Assessing the Impact of Obesity on Pregnancy and Neonatal Outcomes among Saudi Women. Nurs Rep. 2021.11(2):279-290. doi: 10.3390/nursrep11020027.</mixed-citation><mixed-citation xml:lang="en">Adwani N, Fouly H, Omer T. Assessing the Impact of Obesity on Pregnancy and Neonatal Outcomes among Saudi Women. Nurs Rep. 2021.11(2):279-290. doi: 10.3390/nursrep11020027.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Schummers L, Hutcheon JA, Bodnar LM, Lieberman E, Himes KP. Risk of adverse pregnancy outcomes by prepregnancy body mass index: a population-based study to inform prepregnancy weight loss counseling. Obstet Gynecol. 2015;125(1):133-143. DOI: 10.1097/AOG.0000000000000591</mixed-citation><mixed-citation xml:lang="en">Schummers L, Hutcheon JA, Bodnar LM, Lieberman E, Himes KP. Risk of adverse pregnancy outcomes by prepregnancy body mass index: a population-based study to inform prepregnancy weight loss counseling. Obstet Gynecol. 2015;125(1):133-143. DOI: 10.1097/AOG.0000000000000591</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Yang Y, Cai Z, Zhang J. The effect of prepregnancy body mass index on maternal micronutrient status: a meta-analysis. Sci Rep. 2021;11(1):18100. DOI: 10.1038/s41598-021-97635-3</mixed-citation><mixed-citation xml:lang="en">Yang Y, Cai Z, Zhang J. The effect of prepregnancy body mass index on maternal micronutrient status: a meta-analysis. Sci Rep. 2021;11(1):18100. DOI: 10.1038/s41598-021-97635-3</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Scholing JM, Olthof MR, Jonker FA, Vrijkotte TG. Association between pre-pregnancy weight status and maternal micronutrient status in early pregnancy. Public Health Nutr. 2018;21(11):2046-2055. DOI: 10.1017/S1368980018000459</mixed-citation><mixed-citation xml:lang="en">Scholing JM, Olthof MR, Jonker FA, Vrijkotte TG. Association between pre-pregnancy weight status and maternal micronutrient status in early pregnancy. Public Health Nutr. 2018;21(11):2046-2055. DOI: 10.1017/S1368980018000459</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Каронова Т.Л., Шмонина И.А., Андреева А.Т., Байрамов А.А., Беляева О.Д. Дефицит витамина D: причина или следствие ожирения? Consilium Medicum. 2016;18(4):49-52.</mixed-citation><mixed-citation xml:lang="en">Karonova T.L., Shmonina I.A., Andreeva A.T., Bairamov A.A., Beliaeva O.D. Vitamin D deficiency: the cause or the result of obesity? Consilium Medicum. 2016;18(4):49-52. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Веселовская Н.Г., Чумакова Г.А. Ожирение и беременность: сердечно-сосудистые и метаболические риски. Российский кардиологический журнал. 2019;(4):48-52. DOI: 10.15829/1560-4071-2019-4-48-52</mixed-citation><mixed-citation xml:lang="en">Veselovskaya N.G., Chumakova G.A. Obesity and pregnancy: cardiovascular and metabolic risks. Russian Journal of Cardiology. 2019;(4):48-52. (In Russ.) DOI: 10.15829/1560-4071-2019-4-48-52</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Барт Б.Я., Макаров О.В., Рунихина Н.К., Волкова Е.В., Попова Л.В., Андросова Ю.М., и др. Гипертензивные состояния у беременных (социальные и медицинские аспекты). Российский кардиологический журнал. 2010;(3):26-33.</mixed-citation><mixed-citation xml:lang="en">Bart B.Ya., Makarov O.V., Runikhina N.K., Volkova E.V., Popova L.V., Androsova Yu.M., et al. Hypertension in pregnancy: social and medical aspects. Russian Journal of Cardiology. 2010;(3):26-33. (In Russ.)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
