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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">therapeutic</journal-id><journal-title-group><journal-title xml:lang="ru">Южно-Российский журнал терапевтической практики</journal-title><trans-title-group xml:lang="en"><trans-title>South Russian Journal of Therapeutic Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2712-8156</issn><issn pub-type="epub">3033-8344</issn><publisher><publisher-name>РостГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2712-8156-2026-7-1-106-113</article-id><article-id custom-type="elpub" pub-id-type="custom">therapeutic-691</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Случай успешного кардиохирургического лечения пациента с недиагностированной акромегалией</article-title><trans-title-group xml:lang="en"><trans-title>A Case of Successful Cardiac Surgery in a Patient with Undiagnosed Acromegaly. South Russian Journal of Therapeutic Practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3868-8061</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Татаринцева</surname><given-names>З. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Tatarintseva</surname><given-names>Z. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Татаринцева Зоя Геннадьевна, к.м.н., заведующая отделением кардиологии; ассистент кафедры кардиохирургии и кардиологии факультета повышения квалификации и профессиональной переподготовки специалистов</p><p>Краснодар </p></bio><bio xml:lang="en"><p>Zoya G. Tatarintseva, Cand. Sci. (Med.), Head of the Department of Cardiology; Assistant of the Department of Cardiac Surgery and Cardiology of the Faculty of Advanced Training and Professional Retraining of Specialists</p><p>Krasnodar</p></bio><email xlink:type="simple">z.tatarintseva@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-7334-9928</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Катушкина</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Katushkina</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Катушкина Юлия Александровна, врач-эндокринолог эндокринологического отделения; ассистент кафедры терапии №1 факультета повышения квалификации и профессиональной переподготовки специалистов</p><p>Краснодар </p></bio><bio xml:lang="en"><p>Yuliya A. Katushkina, endocrinologist of the endocrinology department; Assistant of the Department of Therapy No. 1 of the Faculty of Advanced Training and Professional Retraining of Specialists</p><p>Krasnodar</p></bio><email xlink:type="simple">ukadoc@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4866-0345</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головина</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovina</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Головина Галина Алексеевна, к.м.н., врач-кардиолог, ассистент кафедры кардиохирургии и кардиологии</p><p>Краснодар </p></bio><bio xml:lang="en"><p>Galina A. Golovina, Cand. Sci. (Med.), cardiologist, assistant of the Department of Cardiac Surgery and Cardiology</p><p>Krasnodar</p></bio><email xlink:type="simple">ggolovina.70@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5690-2482</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Космачева</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kosmacheva</surname><given-names>E. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Космачева Елена Дмитриевна, д.м.н., профессор, заместитель главного врача по лечебной части; заведующая кафедрой терапии №1 ФПК и ППС</p><p>Краснодар </p></bio><bio xml:lang="en"><p>Elena D. Kosmacheva, Dr. Cand. Sci. (Med.), Professor, Deputy Chief Physician for the Medical Department; Head of the Department of Therapy No. 1 of the Faculty of Education and Training</p><p>Krasnodar</p></bio><email xlink:type="simple">kosmachova_h@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «Научно-исследовательский институт – Краевая Клиническая больница № 1 им. проф. С.В. Очаповского» ; ФГБОУ ВО «Кубанский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute – Regional Clinical Hospital No. 1 n. a. Professor S.V. Ochapovsky ; Kuban State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>27</day><month>03</month><year>2026</year></pub-date><volume>7</volume><issue>1</issue><fpage>106</fpage><lpage>113</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Татаринцева З.Г., Катушкина Ю.А., Головина Г.А., Космачева Е.Д., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Татаринцева З.Г., Катушкина Ю.А., Головина Г.А., Космачева Е.Д.</copyright-holder><copyright-holder xml:lang="en">Tatarintseva Z.G., Katushkina Y.A., Golovina G.A., Kosmacheva E.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.therapeutic-j.ru/jour/article/view/691">https://www.therapeutic-j.ru/jour/article/view/691</self-uri><abstract><p>Акромегалия — тяжёлое хроническое нейроэндокринное заболевание, чаще всего встречающееся у взрослых, характеризующееся избытком гормона роста (ГР) и последующим повышением уровня инсулиноподобного фактора роста-1 (ИФР-1). Сердечно-сосудистые осложнения считаются наиболее распространенными осложнениями у пациентов с акромегалией, оказывающие негативное влияние на качество жизни и прогноз. В данной статье представлен случай аневризматического расширения аорты с выраженной аортальной регургитацией у пациента с акромегалией. Пациенту была успешно выполнена операция Бенталла (протезирование аорты и аортального клапана), а через 6 месяцев после кардиохирургического вмешательства проведена транссфеноидальная аденомэктомия без осложнений.</p></abstract><trans-abstract xml:lang="en"><p>Acromegaly is a severe, chronic neuroendocrine disorder, most commonly occurring in adults, characterized by excess growth hormone (GH) and subsequent elevated insulin-like growth factor-1 (IGF-1) levels. Cardiovascular complications are considered the most common complications in patients with acromegaly, negatively impacting quality of life and prognosis. This article presents a case of aneurysmal aortic dilation with severe aortic regurgitation in a patient with acromegaly. The patient underwent a successful Bentall procedure (aortic and aortic valve replacement), and 6 months after cardiac surgery, transsphenoidal adenomectomy was performed without complications.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>акромегалия</kwd><kwd>аневризма восходящей аорты</kwd><kwd>гормон роста</kwd><kwd>инсулиноподобный фактор роста-1</kwd><kwd>пролапс клапана</kwd><kwd>кардиохирургические операции</kwd><kwd>транссфеноидальная аденомэктомия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acromegaly</kwd><kwd>ascending aortic aneurysm</kwd><kwd>growth hormone</kwd><kwd>IGF-1</kwd><kwd>valve prolapse</kwd><kwd>cardiac surgery</kwd><kwd>transsphenoidal adenomectomy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Giustina A, Barkhoudarian G, Beckers A, Ben-Shlomo A, Biermasz N, Biller B, et al. Multidisciplinary management of acromegaly: A consensus. 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