therapeuticЮжно-Российский журнал терапевтической практикиSouth Russian Journal of Therapeutic Practice2712-81563033-8344РостГМУ10.21886/2712-8156-2020-1-3-16-26therapeutic-82Research ArticleОБЗОРЫREVIEWSРезистентная гипертония: фокус на поражение сосудистого руслаResistant hypertension: focus on vascular lesionshttps://orcid.org/0000-0003-2904-0914ЛитвиноваМ. С.LitvinovaM. S.

Литвинова Марина Сергеевна, аспирант кафедры терапии

Ростов-на-Дону

Rostov-on-Don

Litvinova.m.803@mail.ruhttps://orcid.org/0000-0002-2419-4319ХаишеваЛ. А.KhaishevaL. A.

Хаишева Лариса Анатольевна, д.м.н., профессор кафедры терапии

Ростов-на-Дону

Larisa A. Khaisheva, Dr. Sci. (Med.)

Rostov-on-Don

katelnitskay@mail.ruhttps://orcid.org/0000-0003-3070-8424ШлыкС. В.ShlykS. V.

Шлык Сергей Владимирович, д.м.н., профессор, ректор

Ростов-на-Дону 

Sergey V. Shlyk, Dr. Sci. (Med.)

Rostov-on-Don

katelnitskay@mail.ruФГБОУ ВО «Ростовский государственный медицинский университет» Минздрава России; МБУЗ Клинико-диагностический центр «Здоровье»РоссияRostov State Medical University; Clinical and Diagnostic Center «Health»Russian FederationФГБОУ ВО «Ростовский государственный медицинский университет» Минздрава РоссииРоссияRostov State Medical UniversityRussian FederationВО «Ростовский государственный медицинский университет» Минздрава РоссииРоссияRostov State Medical UniversityRussian Federation202005112020131626Copyright © Литвинова М.С., Хаишева Л.А., Шлык С.В., 20202020Литвинова М.С., Хаишева Л.А., Шлык С.В.Litvinova M.S., Khaisheva L.A., Shlyk S.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.therapeutic-j.ru/jour/article/view/82

Понятие резистентной артериальной гипертензии было введено много лет назад и подтверждено в обновленном научном заявлении Американской кардиологической ассоциации (АНА) 2018 и последних рекомендациях Европейского обществ кардиологов (ESC) 2018. Особое внимание к данной группе больных обусловлено высоким риском неблагоприятных исходов по сравнению с контролируемой гипертонией. В настоящем обзоре мы хотим не просто осветить трудности выявления, оценки и оптимизации терапии больных с резистентной АГ, но в большей степени сосредоточиться на основных механизмах формирования истинной резистентности, их выявлении и поиске оптимального пути воздействия.

The concept of resistant arterial hypertension was introduced many years ago and confirmed in the updated scientific statement of the American Heart Association (AHA) 2018 and the latest recommendations of the European Society of Cardiology (ESC) 2018. Special attention to this group of patients is due to the high risk of adverse outcomes compared with controlled hypertension. In this review, we want to highlight not only the difficulties in identifying, assessing and optimizing therapy for patients with RH, but to a greater extent focus on the main mechanisms of the formation of true resistance, their identification and the search for the optimal path of action.

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The authors declare that there are no conflicts of interest present.