Evaluation of the effectiveness of pectin with trepang extract in the complex therapy of NSAID-associated lesions of the upper gastrointestinal tract
https://doi.org/10.21886/2712-8156-2026-7-1-62-68
Abstract
Objective: to evaluate the clinical efficacy of a biologically active pectin supplement with trepang extract in patients with NSAID-associated upper gastrointestinal lesions.
Material and methods: a prospective observational study included patients aged 18–75 years with NSAID-associated upper gastrointestinal lesions. We compared two groups of patients: the first group (n=25) received a combination of standard medications and a pectin complex with trepang extract, while the second group (n=25) received standard therapy in accordance with clinical guidelines.
Results: the group of patients receiving the combination therapy showed statistically significant improvements in treatment outcomes.
Conclusion: the use of a pectin complex with trepang extract as an adjunct to standard therapy enhances the effectiveness of treating NSAID-related gastropathies.
About the Authors
M. V. Mokshina
Pacific State Medical University of the Ministry of Healthcare of Russia
Russian Federation
Russian Federation
Margarita V. Mokshina, Cand. Sci. (Med.), Associate Professor at the Institute of Therapy and Instrumental Diagnostics
Vladivostok
V. A. Nevzorova
Pacific State Medical University of the Ministry of Healthcare of Russia
Russian Federation
Russian Federation
Vera A. Nevzorova, Dr. Sci. (Med.), Professor, Director of the Institute of Therapy and Instrumental Diagnostics
Vladivostok
N. M. Kondrashova
Pacific State Medical University of the Ministry of Healthcare of Russia
Russian Federation
Russian Federation
Nadezhda M. Kondrashova, Cand. Sci. (Med.), Associate Professor at the Institute of Therapy and Instrumental Diagnostics
Vladivostok
A. S. Moskalenko
Primorskaya-kraevaya-klinicheskaya-bolnitsa-№1
Russian Federation
Russian Federation
Aleksandra S. Moskalenko, рostgraduate student of the Department of General and Clinical Pharmacology; Gastroenterologist at the Gastroenterology Department
Vladivostok
E. V. Eliseeva
Pacific State Medical University of the Ministry of Healthcare of Russia
Russian Federation
Russian Federation
Ekaterina V. Eliseeva, Dr. Sci. (Med.), Professor, Head of the Department of General and Clinical Pharmacology
Vladivostok
L. G. Priseko
Pacific State Medical University of the Ministry of Healthcare of Russia
Russian Federation
Russian Federation
Lyudmila G. Priseko, Senior Lecturer at the Institute of Therapy and Instrumental Diagnostics
Vladivostok
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Review
For citations:
Mokshina M.V., Nevzorova V.A., Kondrashova N.M., Moskalenko A.S., Eliseeva E.V., Priseko L.G. Evaluation of the effectiveness of pectin with trepang extract in the complex therapy of NSAID-associated lesions of the upper gastrointestinal tract. South Russian Journal of Therapeutic Practice. 2026;7(1):62-68. (In Russ.) https://doi.org/10.21886/2712-8156-2026-7-1-62-68
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