Nephropathy as a manifestation of multiple myeloma: difficulties in diagnostics in real practice
https://doi.org/10.21886/2712-8156-2025-6-4-132-137
Abstract
Nephropathy is a term used to describe damage or dysfunction of the kidneys, which can ultimately lead to renal failure. At the same time, secondary nephropathies are often encountered in clinical practice, which are not independent kidney diseases, but are complications of the underlying disease. Myeloma nephropathy, which is a serious complication of multiple myeloma, is an example of secondary kidney damage. Often, this pathology is diagnosed when late irreversible complications appear, as a result of which the percentage of treatment effectiveness decreases due to the development of chronic renal failure. In order to optimize the detection of renal disorders and timely initiation of necessary treatment, we present an analysis of a clinical case of a patient suffering from this disease.
About the Authors
A. V. ZvonorenkoRussian Federation
Anastasia V. Zvonorenko, assistant of the Department of Faculty Therapy, Volgograd State Medical University, endocrinologist City Hospital No. 4
Volgograd
M. S. Zvonorenko
Russian Federation
Maksim S. Zvonorenko, assistant of the Department of Faculty Therapy, Volgograd State Medical University, rheumatologist, City Hospital No. 4
Volgograd
T. A. Anipenko
Russian Federation
Tatiana A. Anipenko, head of the Endocrinology Department, endocrinologist of the highest category, nephrologist
Volgograd
A. R. Babaeva
Russian Federation
Aida R. Babaeva, professor, Dr. Sci. (Med.), Head of the Department of Faculty Therapy
Volgograd
References
1. Voitsehovsky V.V., Yesenina T.V., Putintsev D.V., Filatova E.A., Fedorova N.A., Ageenko A.A. et al. Therapy of patients with multiple myeloma complicated by chronic kidney disease. Bulletin physiology and pathology of respiration. 2023;(90): 113-121. (In Russ.) eLIBRARY ID: 58899372 EDN: OVKIXA
2. Zharikov A.S., Leontyev M.V., Bushkovskaya D.A., Fertikova N.S. Biochemical aspects of changes in blood plasma proteins in patients with myeloma. In the collection: Actual issues of modern medical science and health care. Collection of articles of the IX International scientific and practical conference of young scientists and students. 2024;1143-1148. (In Russ.)
3. Kiseleva M.O., Korobkin A.V., Akhmatov V.YU., Grigor'ev T.A., Lyubchenko M.A., Markova YU.A., i dr. Issledovanie vliyaniya dlitel'nosti diagnosticheskogo perioda i soputstvuyushchei patologii kak prediktorov razvitiya mielomnoi nefropatii, trebuyushchei provedeniya programmnogo gemodializa u patsientov s mnozhestvennoi mielomoi, na ehffektivnost' lecheniya. Vestnik Chelyabinskoi oblastnoi klinicheskoi bol'nitsy. 2023;3(57): 19-22. (In Russ.) eLIBRARY ID: 54740644 EDN: LVWWHL
4. Bobkova I.N., Bulanov N.M., Zakharova E.V., Zemchenkov A.Y., Kamyshova E.S., Parshina E.V., et al. KDIGO 2021 Clinical Practice Guideline for the Management of GLOMERULAR Diseases. Nephrology and Dialysis. 2022;24(4):577-874. (In Russ.) doi: 10.28996/2618-9801-2022-4-577-874
5. Kozlovskaya L.V., Rameev V.V., Kogarko I.N., Gordovskaya N.B., Chebotareva N.V., Androsova T.V. et al. Renal lesions associated with monoclonal gammopathies of undetermined significance: clinical forms, mechanisms of development, approaches to treatment. Clinical medicine. 2021;94(12): 892–901. (In Russ.) eLIBRARY ID: 28300547 EDN: XVHVDT
Supplementary files
Review
For citations:
Zvonorenko A.V., Zvonorenko M.S., Anipenko T.A., Babaeva A.R. Nephropathy as a manifestation of multiple myeloma: difficulties in diagnostics in real practice. South Russian Journal of Therapeutic Practice. 2025;6(4):132-137. (In Russ.) https://doi.org/10.21886/2712-8156-2025-6-4-132-137


















