Patient with an unoperated single left ventricle: a clinical case review
https://doi.org/10.21886/2712-8156-2026-7-2-69-75
Abstract
Congenital heart disease in the form of a single left ventricle is a rare congenital pathology, the clinical prognosis of which directly depends on timely surgical intervention. In some patients, the anatomical features of the defect balance pulmonary and systemic blood flow, allowing them to survive into adulthood without surgery. This clinical case report aims to present such a patient, who survived to the age of 29, but with an unfavorable outcome due to additional complicating factors.
About the Authors
G. N. Shemetova
Saratov State Medical University n. a. V.I. Razumovsky
Russian Federation
Russian Federation
Galina N. Shemetova, Dr. Sci. (Med.), Professor, Professor Head of Outpatient Therapy, General Practice and Preventive Medicine
Saratov
V. A. Suraeva
Saratov State Medical University n. a. V.I. Razumovsky
Russian Federation
Russian Federation
Valentina A. Suraeva, assistant Professor of Outpatient Therapy, General Practice and Preventive Medicine
Saratov
R. N. Molodtsov
Saratov State Medical University n. a. V.I. Razumovsky
Russian Federation
Russian Federation
Roman N. Molodtsov, Cand. Sci. (Med.), Associate Professor of Outpatient Therapy, General Practice and Preventive Medicine
Saratov
L. A. Nemtseva
Saratov State Medical University n. a. V.I. Razumovsky
Russian Federation
Russian Federation
Lada A. Nemtseva, a 6th-year student at the Institute of Clinical Medicine, specializing in General Medicine
Saratov
I. Yu. Samsonov
Saratov State Medical University n. a. V.I. Razumovsky
Russian Federation
Russian Federation
Igor Y. Samsonov, 6th year student of the Institute of Clinical Medicine, specialty “Medical Science”
Saratov
References
1. Reller MD, Strickland MJ, Riehle-Colarusso T, Mahle WT, Correa A. Prevalence of congenital heart defects in metropolitan Atlanta, 1998-2005. J Pediatr. 2008;153(6):807-813. DOI: 10.1016/j.jpeds.2008.05.059
2. Burakovsky V.I., Bokeria L.A., eds. Cardiovascular Surgery: A Guide. Moscow: Meditsina; 1996. (In Russ.)
3. Jacobs ML, Mayer JE Jr. Congenital Heart Surgery Nomenclature and Database Project: single ventricle. Ann Thorac Surg. 2000;69(4 Suppl):S197-204. DOI: 10.1016/s0003-4975(99)01245-x
4. Bokeriya L.A., Shatalov K.V., eds. Pediatric Cardiac Surgery: A Guide for Physicians. Moscow: National Medical Research Center of Cardiovascular Surgery, Ministry of Health of the Russian Federation; 2016. (In Russ.)
5. Steinberg EH, Dantzker DR. Single ventricle with severe pulmonary hypertension: natural survival into the third decade of life. Am Heart J. 1993;125(5 Pt 1):1451-1453. DOI: 10.1016/0002-8703(93)91029-e
6. Goldberg HL, Sniderman K, Devereux RB, Levin A. Prolonged survival (62 years) with single ventricle. Am J Cardiol. 1983;52(1):214-215. DOI: 10.1016/0002-9149(83)90102-9
7. Patel MM, Overy DC, Kozonis MC, Hadley-Fowlkes LL. Long-term survival in tricuspid atresia. J Am Coll Cardiol. 1987;9(2):338- 340. DOI: 10.1016/s0735-1097(87)80386-8
8. Mutafyan O. A. Congenital and Acquired Heart Defects in Children and Adolescents: A Guide for Physicians. Moscow: GEOTAR-Media; 2009. (In Russ.)
9. Hallidie-Smith KA, Webb-Peploe MM. Presentation and prognosis of single ventricle. Br Heart J. 1972;34(9):962. PMID: 5075321
10. Rahimtoola SH, Ongley PA, Swan HJ. The hemodynamics of common (or single) ventricle. Circulation. 1966;34(1):14-23. DOI: 10.1161/01.cir.34.1.14
11. Carter BD, Abnet CC, Feskanich D, Freedman ND, Hartge P, Lewis CE, et al. Smoking and mortality--beyond established causes. N Engl J Med. 2015;372(7):631-640. DOI: 10.1056/NEJMsa1407211
12. Schefold JC, Filippatos G, Hasenfuss G, Anker SD, von Haehling S. Heart failure and kidney dysfunction: epidemiology, mechanisms and management. Nat Rev Nephrol. 2016;12(10):610-623. DOI: 10.1038/nrneph.2016.113
13. Nicolas J, Claessen B, Mehran R. Implications of Kidney Disease in the Cardiac Patient. Interv Cardiol Clin. 2020;9(3):265-278. DOI: 10.1016/j.iccl.2020.03.002
14. Beldhuis IE, Lam CSP, Testani JM, Voors AA, Van Spall HGC, Ter Maaten JM, et al. Evidence-Based Medical Therapy in Patients With Heart Failure With Reduced Ejection Fraction and Chronic Kidney Disease. Circulation. 2022;145(9):693- 712. DOI: 10.1161/CIRCULATIONAHA.121.052792
15. Li X, Lindholm B. Cardiovascular Risk Prediction in Chronic Kidney Disease. Am J Nephrol. 2022;53(10):730-739. DOI: 10.1159/000528560
16. Gatzoulis M.A., Webb G.D., Daubeney P.E.F., eds. Diagnosis and Management of Adult Congenital Heart Disease (4th ed.). Elsevier; 2023.
17. Tempe DK, Virmani S. Coagulation abnormalities in patients with cyanotic congenital heart disease. J Cardiothorac Vasc Anesth. 2002;16(6):752-765. DOI: 10.1053/jcan.2002.128436
18. Osthaus WA, Boethig D, Johanning K, Rahe-Meyer N, Theilmeier G, Breymann T, et al. Whole blood coagulation measured by modified thrombelastography (ROTEM) is impaired in infants with congenital heart diseases. Blood Coagul Fibrinolysis. 2008;19(3):220-225. DOI: 10.1097/MBC.0b013e3282f54532
19. Lill MC, Perloff JK, Child JS. Pathogenesis of thrombocytopenia in cyanotic congenital heart disease. Am J Cardiol. 2006;98(2):254- 258. DOI: 10.1016/j.amjcard.2006.01.083
20. Peters AM, Rozkovec A, Bell RN, Hallidie-Smith KA, Goodwin JF, Lavender JP. Platelet kinetics in congenital heart disease. Cardiovasc Res. 1982;16(7):391-397. DOI: 10.1093/cvr/16.7.391
21. Lozano-Espinosa DA, Huertas-Quiñones VM, RodríguezMartínez CE. Impact of pulmonary hypertension and congenital heart disease with hemodynamic repercussion on the severity of acute respiratory infections in children under 5 years of age at a pediatric referral center in Colombia, South America. Cardiol Young. 2020;30(12):1866- 1873. DOI: 10.1017/S1047951120002991
Review
For citations:
Shemetova G.N., Suraeva V.A., Molodtsov R.N., Nemtseva L.A., Samsonov I.Yu. Patient with an unoperated single left ventricle: a clinical case review. South Russian Journal of Therapeutic Practice. 2026;7(2):69-75. (In Russ.) https://doi.org/10.21886/2712-8156-2026-7-2-69-75
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