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HIV-associated polyneuropathy: clinical case

https://doi.org/10.21886/2712-8156-2026-7-1-128-134

Abstract

This article analyzes a clinical observation of a patient with a subacute polyneuropathic syndrome characterized by moderate distal peripheral asymmetric lower paraparesis, calf atrophy, polyneuropathic-type superficial sensitivity disorders in the feet, and deep sensitivity disorders in the feet. During the patient's treatment, a thorough analysis of the patient's complaints and medical history was conducted, and an extensive range of tests was performed, including general clinical, biochemical, cerebrospinal fluid, immunohistochemical, neurophysiological, and magnetic resonance imaging tests. Based on the data obtained, a diagnostic hypothesis was formulated, and a repeated two-fold enzyme-linked immunosorbent assay (ELISA) for human immunodeficiency virus (HIV) was performed, which was negative at the pre-hospital stage. The positive result allowed for the declaration of the patient's neurological symptoms and the formulation of a final clinical diagnosis.

About the Authors

Z. A. Goncharova
Rostov State Medical University
Russian Federation

Zoya A. Goncharova, Dr. Sci. (Med), Professor of the Department of Nervous Diseases and Neurosurgery

Rostov-on-Don 



N. S. Kovaleva
Rostov State Medical University
Russian Federation

Natalia S. Kovaleva, Cand. Sci. (Med.), Associate Professor of the Department of Nervous Diseases and Neurosurgery

Rostov-on-Don 



K. G. Zabaznov
Rostov State Medical University
Russian Federation

Konstantin G. Zabaznov, Cand. Sci. (Med.)

Rostov-on-Don 



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Review

For citations:


Goncharova Z.A., Kovaleva N.S., Zabaznov K.G. HIV-associated polyneuropathy: clinical case. South Russian Journal of Therapeutic Practice. 2026;7(1):128-134. (In Russ.) https://doi.org/10.21886/2712-8156-2026-7-1-128-134

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ISSN 2712-8156 (Print)
ISSN 3033-8344 (Online)