Findings from the EMPEROR-Reduced study are a tool to improve care for patients with chronic heart failure with reduced ejection fraction.Resolution of the Regional Scientific Meeting of Experts of the Southern Federal District
M. M. Batyushin,
A. A. Vachugova,
S. R. Gilyarevskiy,
I. S. Dzherieva,
N. A. Zakaryaeva,
M. V. Zykov,
V. V. Ivanenko,
U. S. Isaeva,
S. G. Kanorskiy,
M. A. Kiseleva,
I. M. Kurbanova,
Yu. M. Lopatin,
S. V. Nedogoda,
G. A. Saneeva,
E. S. Slavickaya,
E. L. Khadartceva https://doi.org/10.21886/2712-8156-2021-2-2-104-110
Abstract
At online scientific expert meeting of the South region held on October 3, 2020, the results of the international multicenter study EMPEROR-Reduced were discussed. Number of proposals and recommendations were adopted for the further study of the cardiovascular and renal effects of empagliflozin, its use in clinical practice in patients with chronic heart failure.
About the Authors
M. M. Batyushin
Rostov State Medical University
Russian Federation
Russian Federation
Mikhail M. Batyushin, Dr. Sci. (Med.), Professor, Professor of Internal Medicine Department №2
Rostov-on-Don
A. A. Vachugova
Volgograd State Medical University
Alla A. Vachugova, Assistant of Internal Medicine Department institute
Volgograd
S. R. Gilyarevskiy
Russian Federation Medical Academy of Continuous Professional Education
Sergey R. Gilyarevskiy, Professor, Professor of Clinical pharmacology and Therapy Department
Moscow
I. S. Dzherieva
Rostov State Medical University
Irina S. Dzherieva, Professor of Internal Medicine Department №2
Rostov-on-Don
N. A. Zakaryaeva
Republic diagnostic center
Nuriyahanum A. Zakaryaeva, Head of Diabetology Department
Makhachkala
M. V. Zykov
Research Institute for Complex Issues of Cardiovascular Diseases
Mikhail V. Zykov, Dr. Sci. (Med.), Leading Researcher
Sochi
V. V. Ivanenko
Volgograd regional clinical cardiological center
Vitaliy V. Ivanenko, Cand. Sci. (Med.)
Volgograd
U. S. Isaeva
Republic endocrinological dispensary
Umulkulsum S. Isaeva, Cand. Sci. (Med.),
Grozniy
S. G. Kanorskiy
Kuban State Medical University
Sergey G. Kanorskiy, Dr. Sci. (Med.), professor, Head of the Department of Internal Medicine № 2 Faculty of Advanced Training and Professional Retraining
Krasnodar
M. A. Kiseleva
Regional cardiology dispensary
Maria A. Kiseleva, Cand. Sci. (Med.)
Astrakhan
I. M. Kurbanova
Republic cardiological ambulatory
Indira M. Kurbanova, Senior Assistant of Emergency Department
Makhachkala
Yu. M. Lopatin
Volgograd State Medical University
Yuri M. Lopatin, Dr. Sci. (Med.), Professor, Head of Cariology, Cardiovascular and Thoracic Surgery Department
S. V. Nedogoda
Volgograd State Medical University
Sergey V. Nedogoda, Dr. Sci. (Med.), Professor, Head of Internal Medicine Department institute
Volgograd
G. A. Saneeva
Stavropol State Medical University
Galina A. Saneeva, Cand. Sci. (Med.), Associate Professor; Associate Professor of the Department of Endocrinology and Pediatric Endocrinology
Stavropol
E. S. Slavickaya
Stavropol State Medical University
Elena S. Slavickaya, Cand. Sci. (Med.)
Stavropol
E. L. Khadartceva
North-Caucasian multidisciplinary medical center
Elena L. Khadartceva, Head of Endocrinology Department
Beslan
References
1. Koudstaal S, Pujades-Rodriguez M, Denaxas S, Gho J, Shah AD, Yu N, et al. Prognostic burden of heart failure recorded in primary care, acute hospital admissions, or both: a population-based linked electronic health record cohort study in 2.1 million people. EurJHeart Fail. 2017;19(9):1119-1127.doi: 10.1002/ejhf.709
2. Jones NR, Roalfe AK, Adoki I, Hobbs FDR, Taylor CJ. Survival of patients with chronic heart failure in the community: a systematic review and meta-analysis. EurJHeartFail.2019;21(11):1306-1325.doi: 10.1002/ejhf.1594
3. Клинические рекомендации ОССН – РКО – РНМОТ. Сердечная недостаточность: хроническая (ХСН) и острая декомпенсированная (ОДСН). Диагностика, профилактикаилечение. Кардиология. 2018;58(S6):8-164. DOI: 10.18087/cardio.2475
4. Mullens W, Damman K, Testani JM, Martens P, Mueller C, Lassus J, et al. Evaluation of kidney function throughout the heart failure trajectory - a position statement from the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2020;22(4):584-603. DOI: 10.1002/ejhf.1697
5. Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, et al. Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. N Engl J Med. 2015;373(22):2117-28. DOI: 10.1056/NEJMoa1504720
6. Packer M. SGLT2 inhibitors produce cardiorenal benefits by promoting adaptive cellular reprogramming to induce a state of fasting mimicry: a paradigm shift in understanding their mechanism of action. Diabetes Care. 2020;43(3):508-511. DOI: 10.2337/dci19-0074
7. McMurray JJV, Solomon SD, Inzucchi SE, Køber L, Kosiborod MN, Martinez FA, et al. Dapagliflozin in patients with heart failure and reduced ejection fraction. N Engl J Med. 2019;381(21):1995-2008.DOI: 10.1056/NEJMoa1911303
8. Packer M, Anker SD, Butler J, Filippatos G, Pocock SJ, Carson P, et al. Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure. N Engl J Med. 2020;383(15):1413-1424.DOI: 10.1056/NEJMoa2022190
9. Neal B, Perkovic V, Mahaffey KW, de Zeeuw D, Fulcher G, Erondu N, et al. Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. N Engl J Med. 2017;377(7):644-657. DOI: 10.1056/NEJMoa1611925
10. Donnan JR, Grandy CA, Chibrikov E, Marra CA, Aubrey-Bassler K, Johnston K, et al. Comparative safety of the sodium glucose co-transporter 2 (SGLT2) inhibitors: a systematic review and meta-analysis. BMJ Open. 2019;9(1):e022577. DOI: 10.1136/bmjopen-2018-022577.
Review
For citations:
Batyushin M.M., Vachugova A.A., Gilyarevskiy S.R., Dzherieva I.S., Zakaryaeva N.A., Zykov M.V., Ivanenko V.V., Isaeva U.S., Kanorskiy S.G., Kiseleva M.A., Kurbanova I.M., Lopatin Yu.M., Nedogoda S.V., Saneeva G.A., Slavickaya E.S., Khadartceva E.L. Findings from the EMPEROR-Reduced study are a tool to improve care for patients with chronic heart failure with reduced ejection fraction.Resolution of the Regional Scientific Meeting of Experts of the Southern Federal District. South Russian Journal of Therapeutic Practice. 2021;2(2):104-110. (In Russ.) https://doi.org/10.21886/2712-8156-2021-2-2-104-110
Views:
1901
Email this article 