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An intensive care case of Goodpasture's syndrome

https://doi.org/10.21886/2712-8156-2023-4-3-94-100

Abstract

A case report of a rare disease associated with antibodies to the basement membrane of the glomeruli of the kidneys (Goodpasture's syndrome) in a young woman is presented. The case is characterized by a typical course of the disease with a high titer of antibodies to the basement membrane of the glomeruli, kidney damage with the formation of terminal renal failure and infiltrative lung damage. The starting point for the development of the disease was probably massive tissue damage after an intense long massage. The diagnosis was confirmed clinically and by immunological data. The patient underwent intensive therapy, including the use of genetic engineering therapy with the subsequent development of covid-19 infection, effectively treated with traditional methods. During the year of observation, stabilization of the autoimmune process was achieved against the background of combination therapy. The difficulty of curing patients with pneumo-renal autoimmune damage and the possibility of achieving a positive course of the disease on the background of multicomponent intensive therapy are emphasized.

About the Authors

L. N. Eliseyeva
Kuban State Medical University
Russian Federation

Eliseyeva Lyudmila N. - Dr. Sci. (Med), Professor, Head of Department of Faculty Therapy.

Krasnodar



V. P. Kurinnaya
Scientific Research Institute – S.V. Ochapovsky Regional Clinic Hospital
Russian Federation

Kurinnaya Valeria P. - nephrologist of the highest category, Head of Department of Nephrology No. 1.

Krasnodar



O. S. Neustroeva
Scientific Research Institute – S.V. Ochapovsky Regional Clinic Hospital
Russian Federation

Neustroeva Olga S. - nephrologist of the highest category, of Nephrology Department No. 1.

Krasnodar



O. V. Maksimovskikh
Scientific Research Institute – S.V. Ochapovsky Regional Clinic Hospital
Russian Federation

Maksimovskikh Olga V. - nephrologist of the highest category of the Nephrology Department No. 1.

Krasnodar



D. N. Malakhova
Scientific Research Institute – S.V. Ochapovsky Regional Clinic Hospital
Russian Federation

Malakhova Darya N. - nephrologist of the second category of the Nephrology Department No 1.

Krasnodar



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For citations:


Eliseyeva L.N., Kurinnaya V.P., Neustroeva O.S., Maksimovskikh O.V., Malakhova D.N. An intensive care case of Goodpasture's syndrome. South Russian Journal of Therapeutic Practice. 2023;4(3):94-100. (In Russ.) https://doi.org/10.21886/2712-8156-2023-4-3-94-100

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ISSN 2712-8156 (Print)