The relationship between sleep duration and cardiometabolic parameters in patients with diabetes mellitus

Objectives: to study the relationship between sleep duration and cardiometabolic parameters in patients with diabetes mellitus.

Materials and methods: the study included patients with type 1 and type 2 diabetes mellitus in the absence of acute metabolic decompensation. The exclusion criteria were: the presence of a depressive episode, the presence of alcohol dependence. In addition, the study did not include patients with cancer, erythrocytosis, sleep apnea syndrome. The duration of the patient’s sleep was determined by answering the question: less than 6 hours, more than 6 hours and up to 8 hours inclusive and more than 8 hours and up to 10 hours inclusive. In addition, the patients were questioned about their compliance with the doctor’s recommendation to take hypolipidemic hypoglycemic and antihypertensive drugs during the last 6 months preceding the survey. Statistical data processing was carried out using the Kolmogorov-Smirnov test. Since the sample was nonparametric, the data are presented by Me (Q25; Q75), where Me is the median, Q25 is the 25th percentile, and Q75 is the 75th percentile, and Spearman’s rank correlation coefficient (P) was calculated to assess the relationship between events.

Results: a total of 92 patients were interviewed. 7 patients were excluded from the sample due to the identification of a depressive episode and four patients due to the presence of alcohol dependence. Thus, the study included 81 patients, of whom 21 patients were observed for type 1 diabetes mellitus and 60 patients for type 2 diabetes mellitus. Spearman’s correlation coefficient showed that there is a direct relationship between sleep duration and HbA1c level (p < 0.01).

Conclusion: in our pilot study, the relationship between the level of glycated hemoglobin as an indicator of compensation for carbohydrate metabolism and sleep duration was confirmed.

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