Comorbid background on the waiting list for liver transplantation. Clinical case of liver cirrhosis as a result of chronic viral hepatitis B with a delta agent in combination with cardiac arrhythmia
https://doi.org/10.21886/2712-8156-2024-5-2-103-109
Abstract
Hepatitis D virus is a dependent virus that depends on hepatitis B virus for replication and transmission. Chronic hepatitis D virus (HDV) is a severe form of viral hepatitis that can lead to end-stage liver disease and hepatocellular carcinoma. Liver transplantation (LT) is the only treatment option for patients with end-stage liver disease, hepatocellular carcinoma, or fulminant hepatitis caused by HDV coinfection. Also, the presence of a comorbid background is associated with a higher rate of complications, longer hospitalization and worse survival both before and after LT. We present a case of liver cirrhosis as a result of HBV+HDV co-infection in combination with arrhythmia in a patient on the waiting list for LT in the Rostov region.
About the Authors
T. M. PetrovaRussian Federation
Tatyana M. Petrova - gastroenterologist of the Gastroenterology Department, of the Regional Center of Surgery and Donor Coordination.
Rostov-on-Don
E. S. Pak
Russian Federation
Ekaterina S. Pak - Cand. Sci. (Med.), Assistant of the Department of Reconstructive, Cardiovascular, Thoracic, Maxillofacial Surgery and Organ Transplantation, RSMU, Head of the Gastroenterology Department, of the Regional Center of Surgery and Donor Coordination, Rostov RCH.
Rostov-on-Don
R. V. Korobka
Russian Federation
Roman V. Korobka - Cand. Sci. (Med.), Associate Professor of the Department of Reconstructive, Cardiovascular, Thoracic, Maxillofacial Surgery and Organ Transplantation, RSMU, Director of the Regional Center of Surgery and Donor Coordination, RRCH.
Rostov-on-Don
V. I. Skachedub
Russian Federation
Victoria I. Skachedub – pathologist.
Rostov-on-Don
O. B. Kucherenko
Russian Federation
Olga В. Kucherenko - assistant of the Department of Radiation Diagnostics, RSMU, head of the X-ray diagnostic department.
Rostov-on-Don
D. V. Pasechnikov
Russian Federation
Dmitry V. Pasechnikov - Cand. Sci (Med), Associate Professor of the Department of Therapy with the Course of Dietetics.
Stavropol
O. V. Bukhtin
Russian Federation
Oleg V. Bukhtin - Resident of the Department of Internal Diseases No. 1.
Rostov-on-Don
References
1. Pisano MB, Giadans CG, Flichman DM, Ré VE, Preciado MV, Valva P. Viral hepatitis update: Progress and perspectives. World J Gastroenterol. 2021;27(26):4018-4044. DOI: 10.3748/wjg.v27.i26.4018
2. Khubutiya M.Sh., Voskanyan S.E., Syutkin V.E., Chulanov V.P., Novruzbekov M.S., Pasechnikov V.D., et al. Recommendations for the prevention and treatment of hepatitis B and C infection in patients on the waiting list for liver transplantation and in liver transplant recipients. Transplantologiya. The Russian Journal of Transplantation. 2020;12(3):231-244. (In Russ.) DOI: 10.23873/2074-0506-2020-12-3-231-244
3. Leise MD, Kim WR, Kremers WK, Larson JJ, Larson JJ, Benson JT, et al. A revised model for end-stage liver disease optimizes prediction of mortality among patients awaiting liver transplantation. Gastroenterology. 2011;140:1952-1960. DOI: 10.1053/j.gastro.2011.02.017
4. Child CG, Turcotte JG. Surgery and portal hypertension. Major Probl Clin Surg. 1964;1:1-85. PMID: 4950264
5. Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Tran-section of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973;60(8):646-649. DOI: 10.1002/bjs.1800600817
6. Vilstrup H, Amodio P, Bajaj J, Cordoba J, Ferenci P, Mullen KD, et al. Hepatic encephalopathy in chronic liver disease: 2014 Practice Guideline by the American Association for the Study of Liver Diseases and the European Association for the Study of the Liver. Hepatology. 2014;60(2):715-735. DOI: 10.1002/hep.27210
7. Moore KP, Wong F, Gines P, Bernardi M, Ochs A, Salerno F, et al. The management of ascites in cirrhosis: report on the consensus conference of the International Ascites Club. Hepatology. 2003;38(1):258-266. DOI: 10.1053/jhep.2003.50315
8. De Franchis R, Bosch J, Garcia-Tsao G, Reiberger T, Ripoll C; Baveno VII Faculty. Baveno VII - Renewing consensus in portal hypertension. J Hepatol. 2022;76(4):959-974. DOI: 10.1016/j.jhep.2021.12.022
9. Korobka V.L., Pasetchnikov V.D., Korobka R.V., Pak E.S., Shapovalov A.M. Use of endoscopic band ligation alone and in combination with nonselective beta blockers for prevention of variceal bleeding in ascites patients on the liver transplant waiting list. Russian Journal of Transplantology and Artificial Organs. 2022;24(3):42-50. (In Russ.) DOI: 10.15825/1995-1191-2022-3-42-50
10. Ivashkin V.T., Maevskaya M.V., Zharkova M.S., Zhigalova S.B., Kitsenko E.A., Manukyan G.V., et al. Clinical Recommendations of the Russian Scientific Liver Society and Russian Gastroenterological Association on Diagnosis and Treatment of Liver Fibrosis, Cirrhosis and Their Complications. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2021;31(6):56-102. (In Russ.)
11. Khatkov I.E., Maev I.V., Bordin D.S., Kucheryavyi Yu.A., Abdulkhakov S.R., Alekseenko S.A., et al. Russian consensus on the diagnosis and treatment of chronic pancreatitis: enzyme replacement therapy. Therapeutic archive. 2017;89(8):80-87. (In Russ.) DOI: 10.17116/terarkh201789880-87
12. Martini S, Tandoi F, Romagnoli R, Rizzetto M. Liver Transplantation in Hepatitis B/Hepatitis D (Delta) Virus Coinfected Recipients, Transplantation. 2022;106(10):1935-1939. DOI: 10.1097/TP.0000000000004138
13. Muhammad H, Tehreem A, Hammami MB, Ting PS, Idilman R, Gurakar A. Hepatitis D virus and liver transplantation: Indications and outcomes. World J Hepatol. 2021;13(3):291-299. DOI: 10.4254/wjh.v13.i3.291
14. Masri NM, Alalwan AM, Aleman S, Alghamdi AS, Alghamdi S, Al-Hamoudi WK, et al. Polaris Observatory. Hepatitis D double reflex testing of all hepatitis B carriers in low-HBV- and high-HBV/HDV-prevalence countries. J Hepatol. 2023;79(2):576-580. DOI: 10.1016/j.jhep.2023.02.041
Supplementary files
Review
For citations:
Petrova T.M., Pak E.S., Korobka R.V., Skachedub V.I., Kucherenko O.B., Pasechnikov D.V., Bukhtin O.V. Comorbid background on the waiting list for liver transplantation. Clinical case of liver cirrhosis as a result of chronic viral hepatitis B with a delta agent in combination with cardiac arrhythmia. South Russian Journal of Therapeutic Practice. 2024;5(2):103-109. (In Russ.) https://doi.org/10.21886/2712-8156-2024-5-2-103-109